94-02-0

Usage

Uses

Used in Organic Synthesis:
Ethyl benzoylacetate is used as an intermediate for different organic synthesis processes. It serves as a key component in the preparation of various organic compounds.
Used in Flavor and Fragrance Industry:
Ethyl benzoylacetate is used as a flavoring agent, providing a sweet, cherry, fruity, and berry-like taste with woody and jammy notes. Its taste threshold values make it suitable for use in food and beverage applications.
Used in Chemical Reactions:
Ethyl benzoylacetate is utilized in chemical reactions such as the synthesis of ethyl 2-fluoro-2-benzolyacetate and the preparation of iodonium ylides. These reactions contribute to the development of new chemical compounds and materials.

Preparation

By condensation of ethyl benzoate with ethyl acetate (via Claisen condensation) using sodium ethoxide; another method also known.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 28, p. 1864, 1985 DOI: 10.1021/jm00150a018Journal of Heterocyclic Chemistry, 32, p. 723, 1995 DOI: 10.1002/jhet.5570320303The Journal of Organic Chemistry, 38, p. 2731, 1973 DOI: 10.1021/jo00955a040

InChI:InChI=1/C11H12O3/c1-2-14-11(13)8-10(12)9-6-4-3-5-7-9/h3-7H,2,8H2,1H3

Upstream product

• 110-89-4 piperidine 
• 60-29-7 diethyl ether 
• 55919-47-6 ethyl 2-bromo-3-oxo-3-phenylpropionate 
• 110-86-1 pyridine 
• 623-73-4 diazoacetic acid ethyl ester 
• 100-52-7 benzaldehyde 
• 93-89-0 benzoic acid ethyl ester 
• 996-82-7 sodium diethylmalonate 
• 1007476-32-5 sodium ethyl acetylacetate enolate 
• 10562-42-2 3,3-dichloro-1-phenyl-propenone 
• 1611-02-5 2-cyano-3-oxo-3-phenyl-propionic acid ethyl ester 
• 95698-20-7 2-hydroxy-4-oxo-2,6-diphenyl-cyclohexanecarboxylic acid ethyl ester 
• 141-52-6 sodium ethanolate 
• 59106-33-1 ethyl 2-bromo-3-phenylacrylate 

Downstream Products

• 21034-21-9 α-benzoyl-γ-butyrolactone 
• 39626-31-8 ethyl 2-benzoyl-3-phenylacrylate 
• 1846-74-8 3-benzoyl-chromen-2-one 
• 117402-91-2 ethyl-2-benzoyl-3,5-diphenyl-5-oxopentanoate 
• 19088-67-6 7-hydroxy-3-(phenylcarbonyl)-2H-chromen-2-one 
• 58792-29-3 3-oxo-1-phenyl-3-piperidin-1-ylpropan-1-one 
• 65847-84-9 β-benzoyloxy-cinnamic acid ethyl ester 
• 141247-91-8 rac-9-(1'-ethoxycarbonyl-2'-phenyl-2'-oxoeth-1'-yl)xanthene 
• 92653-70-8 2-(1-methyl-piperidin-4-yl)-5-phenyl-1,2-dihydro-pyrazol-3-one 
• 113142-82-8 2-benzoyl-4-[2]pyridyl-butyric acid ethyl ester 
• 101089-46-7 1-phenyl-4-pyridin-4-ylbutan-1-one 
• 132856-90-7 1-methyl-2-(1-methyl-piperidin-4-yl)-5-phenyl-1,2-dihydro-pyrazol-3-one 
• 65658-66-4 7-phenyl-2,3-dihydro-1H-imidazo[1,2-a]pyrimidin-5-one 
• 63272-91-3 ethyl 2-benzoyl-3-(pyridin-2-yl)acrylate 

Relevant academic research and scientific papers

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