QSAR study for a novel series of ortho monosubstituted phenoxy analogues of α1-adrenoceptor antagonist WB4101
A number of (S)- and (R)-2-[(2-phenoxyethyl)aminomethyl]-1,4-benzodioxanes unsubstituted or ortho monosubstituted at the phenoxy moiety were synthesized and tested in binding assays on the α1a-AR, α1b-AR, α1d-AR and the 5-
CARBAZOLYL-(4)-OXYPROPANOLAMINE COMPOUNDS AND THERAPEUTIC COMPOSITIONS
Carbazolyl-(4)-oxypropanolamine compounds of the formula where in R1 is hydrogen, lower alkanoyl or aroyl; R2 is hydrogen, lower alkyl or arylalkyl; R3 is hydrogen or lower alkyl; R4is hydrogen or lower alkyl, or when X is oxygen, R4 together with R5 can
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(2008/06/13)
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