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Disodium 4,4'-diaminostilbene-2,2'-disulphonate is an organic compound that serves as an intermediate in the synthesis of 4,4'-diisothiocyano-2,2'-stilbenedisulfonic acid, disodium salt. It is characterized by its ability to inhibit anion transport in various mammalian cell types, such as GABA and Cl-. Additionally, it exhibits fluorescence properties with a maximum absorption wavelength of 341 nm and a maximum emission wavelength of 415 nm in water.

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  • Benzenesulfonic acid,2,2'-(1,2-ethenediyl)bis[5-amino-, sodium salt (1:2)

    Cas No: 7336-20-1

  • USD $ 1.9-2.9 / Gram

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  • 7336-20-1 Structure
  • Basic information

    1. Product Name: disodium 4,4'-diaminostilbene-2,2'-disulphonate
    2. Synonyms: disodium 4,4'-diaminostilbene-2,2'-disulphonate;4,4'-Diaminostilbene-2,2'-disulfonate;Amsonicacidsodiumsalt;Benzenesulfonic acid, 2,2-(1,2-ethenediyl)bis5-amino-, disodium salt;4,4'-Diaminostilben-2,2'-disulfonsure, Dinatriumsalz;4,4''-DIAMINO-2,2''-STILBENEDISULFONIC ACID, DISODIUM SALT;2,2'-(1,2-Ethenediyl)bis(5-aminobenzenesulfonic acid sodium) salt;2,2'-(Ethene-1,2-diyl)bis(5-aminobenzenesulfonic acid sodium) salt
    3. CAS NO:7336-20-1
    4. Molecular Formula: C14H12N2O6S2*2Na
    5. Molecular Weight: 414.36442
    6. EINECS: 230-847-3
    7. Product Categories: N/A
    8. Mol File: 7336-20-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: Dimethylformamide, Water
    9. Water Solubility: 100g/L at 20℃
    10. CAS DataBase Reference: disodium 4,4'-diaminostilbene-2,2'-disulphonate(CAS DataBase Reference)
    11. NIST Chemistry Reference: disodium 4,4'-diaminostilbene-2,2'-disulphonate(7336-20-1)
    12. EPA Substance Registry System: disodium 4,4'-diaminostilbene-2,2'-disulphonate(7336-20-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 7336-20-1(Hazardous Substances Data)

7336-20-1 Usage

Uses

Used in Pharmaceutical Industry:
Disodium 4,4'-diaminostilbene-2,2'-disulphonate is used as an intermediate in the synthesis of 4,4'-diisothiocyano-2,2'-stilbenedisulfonic acid, disodium salt, which has potential applications in the development of drugs targeting anion transport inhibition.
Used in Research Applications:
disodium 4,4'-diaminostilbene-2,2'-disulphonate is utilized in research settings to study the effects of anion transport inhibition on various mammalian cell types, providing valuable insights into the underlying mechanisms and potential therapeutic applications.
Used in HIV Treatment:
Disodium 4,4'-diaminostilbene-2,2'-disulphonate, through its reaction with CD4 glycoprotein on T helper lymphocytes and macrophages, is used as an agent to block HIV type-1 growth at multiple stages of the viral life cycle, offering a potential therapeutic approach for HIV treatment.
Used in Fluorescence-based Assays:
Due to its fluorescence properties, disodium 4,4'-diaminostilbene-2,2'-disulphonate can be employed in fluorescence-based assays for detecting and analyzing anion transport activity in biological systems.

Air & Water Reactions

Water soluble.

Reactivity Profile

disodium 4,4'-diaminostilbene-2,2'-disulphonate is sensitive to iron. .

Fire Hazard

Flash point data for disodium 4,4'-diaminostilbene-2,2'-disulphonate are not available; however, disodium 4,4'-diaminostilbene-2,2'-disulphonate is probably combustible.

Check Digit Verification of cas no

The CAS Registry Mumber 7336-20-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,3,3 and 6 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 7336-20:
(6*7)+(5*3)+(4*3)+(3*6)+(2*2)+(1*0)=91
91 % 10 = 1
So 7336-20-1 is a valid CAS Registry Number.

7336-20-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,4'-diaminostilbene-2,2'-disulfonic acid disodium salt

1.2 Other means of identification

Product number -
Other names DISODIUM 2,2'-ETHENE-1,2-DIYLBIS(5-AMINOBENZENESULFONATE)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7336-20-1 SDS

7336-20-1Relevant articles and documents

Liquid fluorescent whitener and preparation method thereof

-

Paragraph 0071; 0072; 0119; 0120; 0167; 0168, (2017/01/02)

The invention relates to a liquid fluorescent whitener and a preparation method thereof, and belongs to the technical field of special assistants for printing, dyeing and papermaking. A technical problem to be solved is providing the liquid fluorescent whitener and the preparation method thereof. The effective component of the fluorescent whitener is 4,4'-bis[(4-anilino-6-Ramino acid)-1,3,5-triazinyl-2-yl)amino]stilbene-2,2'-tetrasulfonic acid tetrasodium salt, wherein R is a phenyl ring-containing amino acid group. The preparation method comprises the following steps: mixing 4,4'-diaminostilbene-2,2'-disulfonic acid with a NaOH solution to prepare a sodium 4,4'-diaminostilbene-2,2'-disulfonate solution product I, and mixing amino acids with the NaOH solution to prepare an amino acid sodium salt; adding an emulsifier, concentrated hydrochloric acid, cyanuric chloride and sodium sulfanilate to ice water, and reacting to generate a product II; adding the product I to the product II to generate a product III; and adding the amino acid sodium salt to the product III to obtain a crude whitener IV, carrying out pumping filtration, and carrying out desalting concentration to obtain the liquid fluorescent whitener.

Green synthesis of silver nanoparticles using Terminalia cuneata and its catalytic action in reduction of direct yellow-12 dye

Edison, Thomas Nesakumar Jebakumar Immanuel,Lee, Yong Rok,Sethuraman, Mathur Gopalakrishnan

, p. 122 - 129 (2016/04/04)

Facile green synthesis of silver nanoparticles (AgNPs) using aqueous bark extract of Terminalia cuneata has been reported in this article. The effects of concentration of the extract, reaction time and pH were studied by UV-Vis spectroscopy. Appearance of yellow color with λmax around ~ 420 nm suggested the formation of AgNPs. The stable AgNPs were further characterized by Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), dynamic light scattering (DLS) with zeta potential and high resolution transmission electron microscopy (HR-TEM) with energy dispersive X-ray spectroscopy (EDS) analysis. The synthesized AgNPs were in the size range of 25-50 nm with a distorted spherical shape identified from HR-TEM analysis. The catalytic activity of AgNPs on the reduction of direct yellow-12 using NaBH4 was analyzed using a UV-Vis spectrophotometer. This study showed the efficacy of biogenic AgNPs in catalyzing the reduction of direct yellow-12.

PROCESS FOR PREPARATION OF DISODIUM STILBENEDISULFONATES

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Page/Page column 13-14, (2009/03/07)

The present invention relates to a process for preparing sodium benzenesulf onate, more specifically, to a process for preparing sodium benzenesulfonate, which comprises the steps of a) reacting 2-X-4, 6-dichloro-l, 3, 5-triazine with a benzenesulf onic acid, 2, 2- (1, 2-ethenediyl) bis [5-amino] - disodium salt to produce a mixture; b) adding cyanuric chloride to the mixture from a); c) adding the compound, XH to the mixture from b) to produce a benzenesulf onic acid, 2,2'- (1, 2-ethenediyl) bis [5- (4-X-β-chloro-l, 3, 5-triazine-2- yl) amino] disodium salt; and d) separating and purifying the product to obtain the final benzenesulf onic acid, 2, 2'- (1,2- ethenediyl) bis [5- (4-X-β-chloro-l, 3, 5-triazin-2-yl) amino] - disodium salt [wherein, X represents an organic substituent].

Process for the preparation of 4,4'-dinitrostilbene-2,2'-disulfonic acid and its salts

-

, (2008/06/13)

A process for the preparation of 4,4'-dinitrostilbene-2,2'-disulfonic acid and its salts, of the formula STR1 in which M is hydrogen or an alkali metal cation, by oxidation of 4-nitrotoluene-2-sulfonic acid in organic solvents, and also the reduction of the resulting acid or salt, without isolation, to give 4,4'-diamino- or (4-amino-4'-nitro)-stilbene-2,2'-disulfonic acid or salts thereof.

Electrochemical behaviour of bisazodye-chrysophenine

Goyal, R. N.,Kumar, Anoop

, p. 577 - 580 (2007/10/02)

The electrochemical behaviour of the bisazodye-chrysophenine has been studied in the pH range 3.0-10.3 at the dropping mercury electrode and at the pyrolytic graphite electrode.On the basis of polarographic, cyclic voltammetric, coulometric and spectral studies it is concluded that unlike bisazobenzene, where a first 4e, 4H+ process gives the bishydrazo derivative, the cleavage of one of the azo group occurs in this dye.This difference in behaviour is explained on the basis of strongly electron donating substituents present in chrisophenine.The products of electroreduction have been separated and identified.

SYNTHESIS AND TRANSFORMATIONS OF 2,7-DISUBSTITUTED BENZOTHIENOBENZOTHIOPHENES

Zherdeva, S. Yu.,Barudi, A.,Zheltov, A. Ya.,Stepanov, B. I.

, p. 383 - 390 (2007/10/02)

A new method was developed for the synthesis of 2,7-disubstituted benzothienobenzothiophenes by the reaction of 4,4'-disubstituted 2,2'-stilbenedisulfonyl chloride with hydriodic acid and subsequent treatment of the reaction products with perbromopyridinium bromide.From 2,7-dinitrobenzothienobenzothiophene a series of new derivatives containing various electron-donating and electron-withdrawing substituents were obtained.

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