736991-35-8

Basic information

• Product Name: 3-FLUORO-2-(N-MORPHOLINO)-BENZALDEHYDE
• Synonyms: 3-FLUORO-2-(N-MORPHOLINO)-BENZALDEHYDE;3-fluoro-2-morpholin-4-ylbenzaldehyde
• CAS NO: 736991-35-8
• Molecular Formula: C₁₁H₁₂FNO₂
• Molecular Weight: 209.22
• Mol File: 736991-35-8.mol

Chemical Properties

• Boiling Point: 335 ºC at 760 mmHg
• Flash Point: 156.4 ºC
• Appearance: /
• Density: 1.24 g/cm³
• Vapor Pressure: 0.000124mmHg at 25°C
• Refractive Index: 1.563
• PKA: 3.69±0.40(Predicted)
• CAS DataBase Reference: 3-FLUORO-2-(N-MORPHOLINO)-BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-FLUORO-2-(N-MORPHOLINO)-BENZALDEHYDE(736991-35-8)
• EPA Substance Registry System: 3-FLUORO-2-(N-MORPHOLINO)-BENZALDEHYDE(736991-35-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 736991-35-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Fluoro-2-(N-morpholino)-benzaldehyde is used as a building block for the synthesis of pharmaceuticals. Its unique structure allows it to be incorporated into the development of new drugs, potentially leading to the creation of novel therapeutic agents with improved efficacy and selectivity.
Used in Agrochemical Industry:
In the agrochemical industry, 3-Fluoro-2-(N-morpholino)-benzaldehyde serves as a key intermediate in the synthesis of agrochemicals. Its incorporation into these compounds can enhance their performance, leading to more effective pest control and crop protection solutions.
Used in Organic Chemistry Research and Development:
3-Fluoro-2-(N-morpholino)-benzaldehyde is also utilized in research and development within the field of organic chemistry. Its unique properties make it a valuable tool for exploring new chemical reactions and synthesis pathways, potentially leading to the discovery of innovative materials and compounds with a wide range of applications.

InChI:InChI=1/C11H12FNO2/c12-10-3-1-2-9(8-14)11(10)13-4-6-15-7-5-13/h1-3,8H,4-7H2

Upstream product

• 110-91-8 morpholine 
• 2646-91-5 2,3-difluorobenzaldehyde 

Downstream Products

• 1460031-26-8 2,5-dioxopyrrolidin-1-yl 4-{[3-fluoro-2-(morpholin-4-yl)phenyl]methyl}piperazine-1-carboxylate 
• 1446817-45-3 1,1,1,3,3,3-hexafluoropropan-2-yl 4-[[3-fluoro-2-(morpholin-4-yl)phenyl]methyl]piperazine-1-carboxylate 
• 1446818-62-7 4-[2-fluoro-6-(piperazin-1-ylmethyl)phenyl]morpholine 
• 1446818-61-6 tert-butyl 4-[[3-fluoro-2-(morpholin-4-yl)phenyl]methyl]piperazine-1-carboxylate 
• 1356456-03-5 3-[(R)-2-cyclohexyl-4-(3-fluoro-2-morpholin-4-ylbenzyl)-6-oxopiperazin-1-yl]-5-phenylthiophene-2-carboxylic acid 

Relevant articles and documents

CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME

This disclosure provides compounds and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed compunds as at least one active agent. The disclosure also provides for method of treating a patient in need thereof, where the patient is suffering from indications such as pain, solid tumor cancer and/or obesity comprising administering a disclosed compound or composition.

CARBAMATE COMPOUNDS AND OF MAKING AND USING SAME

Provided herein are carbamate compounds which may be useful in the treatment of, for example, pain, solid tumors and/or obesity.

Scope and limitations of the T-reaction employing some functionalized C-H-acids and naturally occurring secondary amines

Scope and limitations of the T-reaction with emphasis on using chiral, natural products as starting materials to prepare novel chiral heterocycles is studied and the diastereoselective introduction of newly formed stereocenters is explained via proposed mechanisms.