2646-91-5

Basic information

• Product Name: 2,3-Difluorobenzaldehyde
• Synonyms: 2,3-DIFLUOROBENZALDEHYDE;TIMTEC-BB SBB006572;2,3-Difluorobenzaldehyde,98%;2,3-Difluorobenzaldehyde 98%;2,5-DIFLUOROBENALDEHYDE;2,3-Difluorobenzalde;2,3-fluorobenzaldehyde;2,3- twofluorobenzeneforMaldehyde
• CAS NO: 2646-91-5
• Molecular Formula: C₇H₄F₂O
• Molecular Weight: 142.1
• EINECS: -0
• Product Categories: Fluorin-contained benzaldehyde series;Fluorobenzene;Carbonyl Compounds;Aromatic Aldehydes & Derivatives (substituted);Aromatic compound;Benzaldehyde;Miscellaneous;Aldehydes;C7;Carbonyl Compounds
• Mol File: 2646-91-5.mol
• Article Data: 7

Chemical Properties

• Melting Point: 64-65 °C
• Boiling Point: 64-65 °C17 mm Hg(lit.)
• Flash Point: 137 °F
• Appearance: Clear pale yellow/Liquid
• Density: 1.301 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0216mmHg at 25°C
• Refractive Index: n20/D 1.499(lit.)
• Storage Temp.: Room temperature.
• Sensitive: Air Sensitive
• BRN: 2961554
• CAS DataBase Reference: 2,3-Difluorobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Difluorobenzaldehyde(2646-91-5)
• EPA Substance Registry System: 2,3-Difluorobenzaldehyde(2646-91-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39-36/37
• RIDADR: UN 1989 3/PG 3
• WGK Germany: 3
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 2646-91-5(Hazardous Substances Data)

Usage

Chemical Properties

clear pale yellow liquid

Uses

2,3-Difluorobenzaldehyde was used in the synthesis of aminophosphine.

General Description

The emission and absorption spectra of 2,3-difluorobenzaldehyde were studied.

InChI:InChI=1/C14H6F8/c1-3-7(15)11(19)5(12(20)8(3)16)6-13(21)9(17)4(2)10(18)14(6)22/h1-2H3

Upstream product

• 3828-49-7 1,2-difluoro-3-methyl-benzene 
• 367-11-3 ortho-difluorobenzene 
• 68-12-2 N,N-dimethyl-formamide 
• 79-46-9 2-nitropropane 
• 113211-94-2 2,3-difluorobenzyl bromide 

Downstream Products

• 784156-92-9 tert-butyl 1-(2,3-difluorobenzyl)-5-oxo-4-(2,2,2-trifluoroethyl)-1,4-diazepan-6-ylcarbamate 
• 845868-01-1 4-[(2,3-difluoro-benzylidene)-amino]-1-methanesulfonyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 412961-26-3 3-(2,3-difluoro-phenyl)-propionic acid 
• 736991-35-8 3-fluoro-2-(morpholin-4-yl)benzaldehyde 
• 1227682-55-4 C₂₅H₁₇ClF₂N₆O₃ 
• 914084-05-2 C₂₀H₂₁F₂NO₃ 
• 914084-13-2 C₂₁H₂₃F₂NO₃ 
• 1426439-16-8 C₂₃H₂₅F₂NO₂ 
• 1426439-17-9 C₂₃H₂₅F₂NO₂ 
• 1426439-06-6 C₁₇H₁₇F₂NO₄ 
• 1166814-39-6 C₁₇H₁₅F₅N₆ 
• 710960-09-1 2-[(4-chlorophenyl)thio]-3-fluorobenzaldehyde 
• 679840-20-1 2,3-difluoro-5-nitrobenzaldehyde 

Relevant articles and documents

Dibenzo seven-membered ring derivative as well as preparation method and application thereof

The invention relates to a dibenzo seven-membered ring derivative as well as a preparation method and application thereof. The chemical structure of the dibenzo seven-membered ring derivative is shownas a formula (I), and X1 and X2 are respectively and independently selected from H, F, Cl, Br or I. The preparation method has easily available raw materials, and can ensure continuous supply and production; the raw materials are cheap and have the cost advantage; and thiophenol or sodium thiophenol is not used, so that the method is more environment-friendly and is also beneficial to the body health of related personnel. 7,8-difluorodibenzo[b,e]thiazepine-11(6H)-one as one of the products can further react to obtain 7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-ol, and the 7,8-difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-ol can be used as an important intermediate for preparing a drug baloxavir, so that baloxavir preparation cost is reduced.

PYRIDINONE DERIVATIVES AS SELECTIVE CYTOTOXIC AGENTS AGAINST HIV INFECTED CELLS

The present disclosure is directed to pyridinone derivatives of Formula I and their use for selectively killing HIV infected GAG-POL expressing cells without concomitant cytotoxicity to HIV nave cells, and for the treatment of infection by HIV, or for the treatment, prophylaxis or delay in the onset or progression of AIDS or AIDS Related Complex (ARC).

Tandem Hass-Bender/Henry reaction for the synthesis of dimethylnitro alcohols from benzylic halides

Dimethylnitro alcohols are constructed in a one-pot process from benzylic halides and 2-nitropropane. The use of tetrabutylammonium fluoride (TBAF) as the promoter is essential for this tandem Hass-Bender/Henry reaction to proceed.