739366-03-1

Basic information

• Product Name: 1H-Pyrazol-3-amine,5-(methoxymethyl)-(9CI)
• Synonyms: 1H-Pyrazol-3-amine,5-(methoxymethyl)-(9CI);5-(Methoxymethyl)-1H-pyrazol-3-amine;5-Amino-3-(methoxymethyl)-1H-pyrazole;3-AMino-5-MethoxyMethyl-1H-pyrazole;3-(Methoxymethyl)-1H-pyrazol-5-amine
• CAS NO: 739366-03-1
• Molecular Formula: C5H9N3O
• Molecular Weight: 127.146
• Product Categories: PYRAZOLE;AMINEPRIMARY
• Mol File: 739366-03-1.mol

Chemical Properties

• Boiling Point: 322.1±27.0 °C(Predicted)
• Appearance: /
• Density: 1.241±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 14?+-.0.10(Predicted)
• CAS DataBase Reference: 1H-Pyrazol-3-amine,5-(methoxymethyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazol-3-amine,5-(methoxymethyl)-(9CI)(739366-03-1)
• EPA Substance Registry System: 1H-Pyrazol-3-amine,5-(methoxymethyl)-(9CI)(739366-03-1)

Safety Data

• Hazardous Substances Data: 739366-03-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1H-Pyrazol-3-amine,5-(methoxymethyl)-(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs targeting a range of diseases and conditions. Its unique chemical structure and reactivity are instrumental in creating novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 1H-Pyrazol-3-amine,5-(methoxymethyl)-(9CI) is utilized as a precursor in the creation of compounds that can be applied in crop protection and other agricultural applications, leveraging its chemical properties to enhance the effectiveness of these products.
Used in Organic Synthesis:
1H-Pyrazol-3-amine,5-(methoxymethyl)-(9CI) is employed as a versatile intermediate in organic synthesis, where its distinctive structure allows for the formation of a variety of complex organic compounds through different chemical reactions, broadening its applications in the field of chemistry and chemical engineering.

Upstream product

• 67-56-1 methanol 
• 1000895-25-9 (5-nitro-1H-pyrazol-3-yl)methanol 
• 739366-02-0 4-methoxy-3-oxo-butyronitrile 

Downstream Products

• 739366-04-2 ethyl 2-methoxymethylpyrazolo[1,5-a]pyrimidine-6-carboxylate 

Relevant articles and documents

NOVEL PYRAZOLO-PYRROLO-PYRIMIDINE-DIONE DERIVATIVES AS P2X3 INHIBITORS

The present invention covers substituted Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.

COMPOUND INHIBITING DIPEPTIDYL PEPTIDASE IV

The invention aims to provide a dipeptidyl peptidase IV inhibitor which is satisfactory in respect of activity, stability and safety and has an excellent action as a pharmaceutical agent. The invention is directed to a compound represented by the following general formula or a pharmaceutically acceptable salt thereof: wherein R1 and R2 each represents hydrogen, an optionally substituted C1-6 alkyl group, or -COOR5 whereupon R5 represents hydrogen or an optionally substituted C1-6 alkyl group, or R1 and R2, together with a carbon atom to which they are bound, represent a 3- to 6-membered cycloalkyl group, R3 represents hydrogen or an optionally substituted C6-10 aryl group, R4 represents a hydrogen or a cyano group, D represents -CONR6-, -CO- or -NR6CO-, R6 represents hydrogen or an optionally substituted C1-6 alkyl group, E represents -(CH2)m- whereupon m is an integer of 1 to 3, -CH2OCH2-, or -SCH2-, n is an integer of 0 to 3, and A represents an optionally substituted bicyclic heterocyclic group or bicyclic hydrocarbon group.