Formation of 2-sulphamoylacetylphenol from zonisamide under aerobic conditions in rat liver microsomes
1. The antiepileptic agent zonisamide, 1,2-benzisoxazole-3- methanesulphonamide, was metabolized reductively to 2-sulphamoyl- acetylphenol (SMAP) not only under anaerobic conditions but also under aerobic conditions in liver microsomes of rat pretreated w
COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGIC DISEASES AND NEUROLOGICAL DISORDERS
The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of
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Paragraph 00100-00101
(2014/05/24)
Studies on 3-substituted 1,2-benzisoxazole derivatives. VII. Catalytic reduction of 3-sulfamoylmethyl-1,2-benzisoxazole and reactions of the resulting products
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Uno,Kurokawa
p. 333 - 335
(2007/10/02)
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