74702-89-9

Basic information

• Product Name: 1-(3-Fluorophenyl)-1-MethylethylaMine
• Synonyms: 1-(3-Fluorophenyl)-1-MethylethylaMine;2-(3-fluorophenyl)propan-2-aMine
• CAS NO: 74702-89-9
• Molecular Formula: C₉H₁₂FN
• Molecular Weight: 153.1966832
• Mol File: 74702-89-9.mol

Chemical Properties

• Boiling Point: 199.6±15.0 °C(Predicted)
• Appearance: /
• Density: 1.038±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 9.04±0.10(Predicted)
• CAS DataBase Reference: 1-(3-Fluorophenyl)-1-MethylethylaMine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-Fluorophenyl)-1-MethylethylaMine(74702-89-9)
• EPA Substance Registry System: 1-(3-Fluorophenyl)-1-MethylethylaMine(74702-89-9)

Safety Data

• Hazardous Substances Data: 74702-89-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(3-Fluorophenyl)-1-Methylethylamine is used as a psychoactive stimulant for its ability to increase alertness, wakefulness, and focus. It is utilized in the development of medications aimed at treating conditions that involve fatigue, lack of concentration, or mood disorders.
Used in Research and Development:
In the scientific community, 1-(3-Fluorophenyl)-1-Methylethylamine serves as a research compound for studying the effects of phenethylamines and their derivatives on the central nervous system. This helps in understanding the mechanisms of action and potential therapeutic applications of similar compounds.
Used in Forensic Toxicology:
1-(3-Fluorophenyl)-1-Methylethylamine may also be used in forensic toxicology for the identification and analysis of substances in biological samples. This aids in investigations related to substance abuse or poisoning cases.

Upstream product

• 401-76-3 2-(3-fluorophenyl)propan-2-ol 
• 455-36-7 1-(3-fluorophenyl)ethanone 

Downstream Products

• 1422208-38-5 C₂₄H₃₃FN₂O₃ 
• 1422207-59-7 C₃₃H₄₂FN₃O₃ 
• 1422208-53-4 C₁₉H₂₅FN₂O*ClH 

Relevant articles and documents

One-Pot C-H Arylation/Lactamization Cascade Reaction of Free Benzylamines

An efficient method has been developed for the synthesis of seven-membered biaryl lactams involving Pd-catalyzed, native amine-directed, ortho-arylation of benzylamines followed by in situ lactamization. This cascade sequence is enabled by the use of 2-iodobenzoates, which facilitates C-H arylation from the free amine under conditions that typically require an improved directing group approach. This reaction is characterized by a broad substrate scope with good functional group tolerance. The need for an ester versus carboxylic acid-functionalized coupling partner is also explored, as is the potential for synthesizing eight-membered biaryl lactams. Various applications are also investigated, including access to the aza-brassinolide core.

Synthesis of 4H-1,3-Benzoxazines via Metal- and Oxidizing Reagent-Free Aromatic C-H Oxygenation

An unprecedented electrochemical aromatic C-H oxygenation reaction for the synthesis of 4H-1,3-benzoxazines from easily available N-benzylamides is reported. These oxidative cyclization reactions proceed in a transition metal- and oxidizing reagent-free fashion and produce H2 as only theoretical byproduct. Adapting the C-H oxygenation reaction in an electrochemical microreactor has been demonstrated.

NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND

The present invention provides a compound represented by the following formula (I) or its pharmaceutically acceptable salt: [wherein, R1 represents optionally substituted C1-4 alkyl, n shows integer of 1 to 4, R2 represents optionally substituted C1-4 alkyl or hydrogen atom, R3 represents optionally substituted C1-4 alkyl, R4a, R4b, R4c, and R4d, similarly or differently, represent optionally substituted C6-14 aryl, optionally substituted C1-4 alkyl, or hydrogen atom and the like, A represents optionally substituted C6-14 aryl or optionally substituted 5 to 11 membered heteroaryl].