455-36-7

Basic information

• Product Name: 3'-Fluoroacetophenone
• Synonyms: Ethanone, 1-(3-fluorophenyl)-;3'-Fluoroacetophenone ,97%;3-fluorohypnone;Acetophenone, 3'-fluoro-;1-(3-FLUOROPHENYL)ETHAN-1-ONE;1-(3-FLUOROPHENYL)ETHANONE;3'-FLUOROACETOPHENONE;3-FLUOROACETOPHENONE
• CAS NO: 455-36-7
• Molecular Formula: C₈H₇FO
• Molecular Weight: 138.14
• EINECS: 207-245-4
• Product Categories: Benzene series;Fluorobenzene;ketone;Adehydes, Acetals & Ketones;Fluorine Compounds;C7 to C8;Carbonyl Compounds;Ketones;Acetophenone series;Aryl Fluorinated Building Blocks;Building Blocks;C7 to C8;C7-C8;Carbonyl Compounds;Chemical Synthesis;Fluorinated Building Blocks;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks;Aromatic Acetophenones & Derivatives (substituted)
• Mol File: 455-36-7.mol
• Article Data: 50

Chemical Properties

• Melting Point: -3°C
• Boiling Point: 81 °C9 mm Hg(lit.)
• Flash Point: 177 °F
• Appearance: Clear colorless to yellow/Liquid
• Density: 1.126 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.27mmHg at 25°C
• Refractive Index: n20/D 1.509(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• Water Solubility: Slightly soluble in water.
• BRN: 907041
• CAS DataBase Reference: 3'-Fluoroacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-Fluoroacetophenone(455-36-7)
• EPA Substance Registry System: 3'-Fluoroacetophenone(455-36-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-36/37/39-27
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 455-36-7(Hazardous Substances Data)

Usage

Chemical Properties

clear colourless to yellow liquid

Uses

3'-Fluoroacetophenone is used as raw material and intermediate in Organic Synthesis, Pharmaceuticals, Agrochemicals and Dyestuffs.

General Description

Bioreduction of 3′-fluoroacetophenone by cells of Aspergillus terreus in phosphate buffer solution-glycerol has been reported.

InChI:InChI=1/C8H7FO/c1-6(10)7-3-2-4-8(9)5-7/h2-5H,1H3

Upstream product

• 402-63-1 1-(3-fluorophenyl)ethanol 
• 99-03-6 1-(3-aminophenyl)ethanone 
• 1711-07-5 3-fluorobenzoyl chloride 
• 98-86-2 acetophenone 
• 1121-86-4 1-Fluoro-3-iodobenzene 
• 75-36-5 acetyl chloride 
• 1073-06-9 3-fluorobromobenzene 
• 111-34-2 -butyl vinyl ether 
• 1336-21-6 ammonium hydroxide 
• 2561-17-3 1-ethynyl-3-fluoro-benzene 
• 214360-49-3 1-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-ethanone 
• 149104-90-5 4-acetylphenylboronic acid 
• 171364-81-1 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanone 
• 768-35-4 3-fluorophenylboronic acid 

Downstream Products

• 2378-25-8 (E)-1-(3-fluorophenyl)-3-phenylprop-2-en-1-one 
• 52186-49-9 α-(Trimethylsiloxy)-m-fluorstyrol 
• 147218-00-6 N-<1-(3-fluorophenyl)ethylidene>-2-(trifluoromethyl)aniline 
• 139040-55-4 2-(3-Fluoro-phenyl)-2-hydroxy-N,N-dimethyl-thiopropionamide 
• 91842-71-6 1-(3-Fluoro-phenyl)-ethylidene-oxonium 
• 98-86-2 acetophenone 
• 455-38-9 3-fluorobenzoic acid 
• 175846-99-8 N-<1-(3-fluorophenyl)ethylidene>-2-(trifluoromethyl)aniline 
• 53631-18-8 2-bromo-1-(3-fluorophenyl)ethanone 
• 582325-02-8 3-(dimethylamino)-1-(3-fluorophenyl)propan-1-one 
• 125997-01-5 1-(3-fluorophenyl)-4-penten-1-one 
• 372-20-3 3-fluorophenol 
• 701-83-7 3-fluorophenyl acetate 
• 936231-60-6 1-(3-fluoro-phenyl)-1-(2-methyl-[1,3]dithian-2-yl)-ethanol 

Relevant articles and documents

Visible light-mediated, high-efficiency oxidation of benzyl to acetophenone catalyzed by fluorescein

An environmentally friendly aerobic oxidation of benzyl C(sp3)-H bonds to ketones via selective oxidation catalysis was developed. Fluorescein is an efficient photocatalyst with excellent chemical selectivity. The reaction has a wide substrate scope, and a successful gram-scale experiment demonstrated its potential industrial utility.

Promoting charge separation in donor-acceptor conjugated microporous polymers: Via cyanation for the photocatalytic reductive dehalogenation of chlorides

Conjugated microporous polymers (CMPs) have emerged as promising heterogeneous photocatalysts for organic transformations owing to their structural designability and functional versatility. However, limited by the insufficient separation of the photo-generated excitons, their photocatalytic efficiency falls far short of expectations. Herein, we demonstrate a cyanation strategy to promote charge carrier separation in CMPs by selectively incorporating carbazole and cyano groups as electron-donating and electron-withdrawing units, respectively. The resulting CMPs feature π-extended donor (D)-acceptor (A) conjugation structures endowing them with distinct semiconducting properties, in which the efficient charge separation and transfer and wide visible-light absorption are facilitated. Compared to the cyano-free counterpart, the cyano-functionalized CMPs showed superior photocatalytic efficiency as exemplified by photocatalytic reductive dehalogenation of chlorides. More prominently, full recyclability of the designed CMPs as well as catalytic activity for at least ten runs without the loss of catalytic performance in photocatalytic reductive dehalogenation of chlorides demonstrated their robustness and sustainability. This journal is

A sodium trifluoromethanesulfinate-mediated photocatalytic strategy for aerobic oxidation of alcohols

A sodium trifluoromethanesulfinate-mediated photocatalytic strategy for the aerobic oxidation of alcohols has been developed for the first time, and the photoredox aerobic oxidation of secondary and primary alcohols provided the corresponding ketones and carboxylic acids, respectively, in high to excellent yields.