Synthesis of Sulfoximidoyl-Containing Hypervalent Iodine(III) Reagents and Their Use in Transition-Metal-Free Sulfoximidations of Alkynes
Well-defined hypervalent iodine(III) reagents incorporating transferable sulfoximidoyl groups were obtained through ligand exchange reactions of methoxy(tosyloxy)iodobenzene (MTIB) with NH sulfoximines in good to excellent yields. The solid-state structure of a representative product was characterized by X-ray crystallography. Utilizing these reagents in synthesis provides a new, transition-metal-free approach towards N-alkynylated sulfoximines.