- New benzene derivative compd. and cosmetic composition using the same
-
PROBLEM TO BE SOLVED: To provide a novel benzenediol derivative compound exhibiting excellent whitening activity by strong inhibition of melanogenesis, and to provide a composition for skin whitening containing the same.SOLUTION: A benzenediol derivative for skin whitening represented by a general formula (I) is provided, where A is derived from an aromatic compound, C1 and C2 are derived from a cyclic compound in which two hydroxy groups are each bound at either position 1 and position 3 (meta-position) or position 1 and position 4 (para-position), R1 and R2 are linear or branched saturated or unsaturated acyl groups, and R3, R4, R5 and R6 are each at least one substituent independently selected from a group consisting of a hydrogen, an alkyl group, an alkoxy group, an acyl group, a hydroxy group, a vinyl group, a nitrile group, a carboxyaldehyde group and an aldehyde group.
- -
-
Paragraph 0023
(2019/03/29)
-
- DERIVATIVE OF NOVEL POLYHYDROXY AROMATIC COMPOUND AND USE THEREOF
-
Provided is a skin whitening composition with excellent whitening effects, specifically, a derivative or a polyhydroxy cyclic compound represented by Formula I or a pharmacologically acceptable salt thereof, comprising; wherein is derived from an aromatic
- -
-
-
- Ytterbium triflate catalysed Friedel-Crafts reaction using carboxylic acids as acylating reagents under solvent-free conditions
-
The Friedel-Crafts acylation of 1-naphthol and phenol derivatives with carboxylic acids were investigated by using a catalytic amount of metal-triflate, in particular Yb(OTf)3, under solvent-free conditions. Both aliphatic and aromatic carboxylic acids reacted easily to afford the corresponding hydroxyaryl ketones.
- Jin, Can,Li, Jie,Su, Weike
-
experimental part
p. 607 - 611
(2011/02/26)
-