A microwave-assisted facile one-pot synthesis of annelated pyridines from β-formyl enamides via henry reaction
The base-catalysed solid phase condensation of β-formyl enamides with nitromethane under microwave irradiation afforded a novel one-pot synthesis of pyridines via Henry reaction.
Chetia, Apurba,Longchar, Moanochet,Lekhok, Kushal C.,Boruah, Romesh C.
An Investigation of the Reaction of 2-Aminobenzaldehyde Derivatives with Conjugated Nitro-olefins: An Easy and Efficient Synthesis of 3-Nitro-1,2-dihydroquinolines and 3-Nitroquinolines
2-Aryl-3-nitro-1,2-dihydroquinolines 3 were prepared from the reaction of β-nitrostyrenes 2 and 2-aminobenzaldehyde 1 in the presence of DABCO. Not only β-nitrostyrenes but other alkyl nitro olefins also can be used in this reaction as well. When DDQ or silica gel was added to a solution of 3-nitro-1,2-dihydroquinolines 3, 3-nitro-2-substituted-quinolines 4 were obtained. When 2-aminobenzaldehyde derivatives 7 and 12 were reacted with β-nitrostyrenes 2, unique rearrangement products were produced.