cas 76117-70-9, (E)-4-Acetoxy Tamoxifen | Articles data ｜lookchem

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76117-70-9

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ERR MODULATORS AND USES THEREOF
Disclosed herein, inter alia, are compositions and methods useful for treating non-alcoholic fatty liver diseases.
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Paragraph 0492; 0493; 0494

(2018/11/21)

Quaternary ammonium-linked glucuronidation of trans-4-hydroxytamoxifen, an active metabolite of tamoxifen, by human liver microsomes and UDP-glucuronosyltransferase 1A4
Tamoxifen (TAM), a nonsteroidal antiestrogen, is the most widely used drug for chemotherapy of hormone-dependent breast cancer in women. Trans-4-hydroxy-TAM (trans-4-HO-TAM), one of the TAM metabolites in humans, has been considered to be an active metabo
Ogura, Kenichiro,Ishikawa, Yuko,Kaku, Teppei,Nishiyama, Takahito,Ohnuma, Tomokazu,Muro, Kei,Hiratsuka, Akira
p. 1358 - 1369
(2007/10/03)

Compounds and methods for treating breast cancer and other diseases
Disclosed are novel compositions and novel methods for the creation of both the novel compounds and known compounds. Also disclosed are methods for use of the novel compounds for treating a variety of diseases relating to decreasing or preventing activati
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Page/Page column 18

(2008/06/13)

More Articles about upstream products of 76117-70-9

Chemical Properties

Melting Point: 98-100°C
Solubility:Dichloromethane, Ethyl Acetate, Methanol
Storage Temp.:Amber Vial, -20°C Freezer
PSA: 38.77000
LogP: 5.92140

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