- CYCLIC 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS
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Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-Beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure (I) enantiomers, diastereomers, solvates, or salts thereof, wherein A, W, X and Z are defined herein.
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Page/Page column 78-79
(2008/06/13)
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- Solvolysis of 2-Aryl-2-chloroadamantanes. A new Y Scale for Benzylic Chlorides
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A series of 2-aryl-2-chloroadamantanes 2, Ar = 4'-methylphenyl, 4'-fluorophenyl, phenyl, 3'-chlorophenyl, 3'-(trifluoromethyl)phenyl, and 4'-(trifluoromethyl)phenyl, were prepared, and the solvolytic rate constants in 23 solvents were measured.Significant
- Liu, Kwang-Ting,Sheu, Hun-Chang
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p. 3021 - 3025
(2007/10/02)
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