76481-44-2

Upstream product

• 700-58-3 2-Adamantanone 
• 352-13-6 4-flourophenylmagnesium bromide 
• 352-33-0 1-Chloro-4-fluorobenzene 

Downstream Products

• 287173-16-4 2-(4-Fluorophenyl)-2-adamantanemethanamine hydrochloride 
• 233669-17-5 2-(4-fluorophenyl)-2-adamantanecarbonitrile 
• 130486-50-9 2-chloro-2-(4'-fluorophenyl)adamantane 

Relevant academic research and scientific papers

CYCLIC 11-BETA HYDROXYSTEROID DEHYDROGENASE TYPE I INHIBITORS

Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-Beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure (I) enantiomers, diastereomers, solvates, or salts thereof, wherein A, W, X and Z are defined herein.

Solvolysis of 2-Aryl-2-chloroadamantanes. A new Y Scale for Benzylic Chlorides

A series of 2-aryl-2-chloroadamantanes 2, Ar = 4'-methylphenyl, 4'-fluorophenyl, phenyl, 3'-chlorophenyl, 3'-(trifluoromethyl)phenyl, and 4'-(trifluoromethyl)phenyl, were prepared, and the solvolytic rate constants in 23 solvents were measured.Significant