Synthesis and &β-Adrenergic Blocking Activity of 1--4-arylpiperazines
Condensation of thymol (II) with epichlorohydrin gives the corresponding glycidyl ether (III) which on treatment with N-arylpiperazines furnishes 1--4-arylpiperazines (IVa-g).These compounds (IVa-g) have been found to exhibit hypotensive activity.
Samant, S. D.,Gupte, S. M.,Kulkarni, R. A.
p. 524 - 525
(2007/10/02)
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