- Method of synthesizing 4-decenoic acid
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The invention discloses a method of synthesizing 4-decenoic acid, including the following steps: performing heat reflux with 1-octylene-3-ol and ortho-acetate as raw materials in presence of a catalyst, distilling generated ethanol out at the same time, performing reduced pressure distillation to remove excessive ortho-acetate, and finally rectifying the product to obtain pure 4-decenoate; performing heat reflux to the 4-decenoate under an alkaline condition and distilling hydrolyzed alcohol compounds out, regulating the pH to 7, extracting and distilling the liquid, and finally rectifying the liquid to obtain pure 4-decenoic acid. The pure 4-decenoic acid is prepared through a Claisen rearrangement reaction. The synthesis process is simple.
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Paragraph 0021; 0023; 0025
(2017/08/29)
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- Transforming Olefins into γ,δ-Unsaturated Nitriles through Copper Catalysis
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We have developed a strategy to transform olefins into homoallylic nitriles through a mechanism that combines copper catalysis with alkyl nitrile radicals. The radicals are easily generated from alkyl nitriles in the presence of the mild oxidant di-tert-butyl peroxide. This cross-dehydrogenative coupling between simple olefins and alkylnitriles bears advantages over the conventional use of halides and toxic cyanide reagents. With this method, we showcase the facile synthesis of a flavoring agent, a natural product, and a polymer precursor from simple olefins.
- Wu, Xuesong,Riedel, Jan,Dong, Vy M.
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supporting information
p. 11589 - 11593
(2017/09/11)
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- Iminyl, Amidyl, and Carbamyl Radicals from O-Benzoyl Oximes and O-Benzoyl Hydroxamic Acid Derivatives.
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Oxime benzoates and O-benzoyl hydroxamic acid derivatives react with tributylstannane in the presence of AIBN to give iminyl, amidyl, and carbamyl radicals which can be captured by an internal olefin.
- Boivin, Jean,Callier-Dublanchet, Anne-Claude,Quiclet-Sire, Beatrice,Schiano, Anne-Marie,Zard, Samir Z.
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p. 6517 - 6528
(2007/10/02)
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- METATHESIS OF FUNCTIONAL DERIVATIVES OF OLEFINS BY THE ACTION OF THE WCl6-1,1,3,3-TETRAMETHYL-1,3-DISILACYCLOBUTANE CATALYTIC SYSTEM
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A study was carried out on the metathesis of esters of unsaturated carboxylic acids and nitriles by the action of the WCl6-1,1,3,3-tetramethyl-1,3-disilacyclobutane catalytic system.The possibility of efficient homometathesis and cometathesis with α-olefins and allyltrimethylsilane was demonstrated for ethyl 4-pentenoate and allyl cyanide.
- Bespalova, N. B.,Bovina, M. A.
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p. 156 - 159
(2007/10/02)
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- Selectivity of Radical Formation in the Reaction of Carbonyl Compounds with Manganese(III) Acetate
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The selectivity of radical generation in the oxidation of carbonyl compounds by manganese(III) has been studied in two ways.Competitive reaction of acetic and propionic acids under conditions in which the resultant radicals are trapped efficiently by an alkene suggests that propionic acid reacts some 3.8 times more readily than does acetic acid.Oxidation of butanone under similar conditions gives products in the formation of which reaction has occurred 2.9 times more readily at C-3 of butanone than at C-1.However, this ratio reflects a combination of chain propagation and of initiation by manganese(III) oxidation.When propagation is effectively eliminated, the C-1 position is the more reactive.The significance of these observations on the mechanism of oxidation of carbonyl compounds by manganese(III) is discussed.It is suggested that enol radical-cations can be formed in the reaction but that these do not give carbonyl-stabilised radicals by deprotonation.
- Midgley, Gary,Thomas, C. Barry
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p. 1103 - 1108
(2007/10/02)
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- PALLADIUM CATALYZED ALLYLATION OF REFORMATSKY REAGENTS. SYNTHESIS OF γ,δ-UNSATURATED ESTERS.
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Reformatsky reagents regioselectively react under mild conditions with allylic acetates in the presence of Pd(PPh3)4 to give γ,δ-unsaturated esters in good yields.
- Boldrini, Gian Paolo,Mengoli, Marina,Tagliavini, Emilio,Trombini, Claudio,Umani-Ronchi, Achille
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p. 4223 - 4226
(2007/10/02)
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