766539-28-0

Basic information

• Product Name: 2-CARBOXYMETHYL-MORPHOLINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER
• Synonyms: 2-CARBOXYMETHYL-MORPHOLINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER;2-(4-N-BOC-MORPHOLIN-2-YL)ACETIC ACID;4-BOC-MORPHOLINE-2-ACETIC ACID;N-BOC-MORPHOLINE-2-A(1-AMINO-CYCLOHEXYL)-ACETIC ACID METHYL ESTERCETIC ACID ;4-Boc-2-morpholineacetic acid;N-BOC-MORPHOLINE-2-ACETIC ACID;2-{4-[(tert-butoxy)carbonyl]Morpholin-2-yl}acetic acid
• CAS NO: 766539-28-0
• Molecular Formula: C11H19NO5
• Molecular Weight: 245.27
• Product Categories: pharmacetical
• Mol File: 766539-28-0.mol

Chemical Properties

• Boiling Point: 388.2 °C at 760 mmHg
• Flash Point: 188.6 °C
• Appearance: /
• Density: 1.179 g/cm³
• Vapor Pressure: 4.16E-07mmHg at 25°C
• Refractive Index: 1.482
• Storage Temp.: 2-8°C
• PKA: 4.31±0.10(Predicted)
• CAS DataBase Reference: 2-CARBOXYMETHYL-MORPHOLINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CARBOXYMETHYL-MORPHOLINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER(766539-28-0)
• EPA Substance Registry System: 2-CARBOXYMETHYL-MORPHOLINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER(766539-28-0)

Safety Data

• Hazard Codes: T
• Statements: 25-51
• Safety Statements: 45
• Hazardous Substances Data: 766539-28-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Development:
2-Carbomethyl-morpholine-4-carboxylic Acid Tert-Butyl Ester is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable component in the creation of new drugs.
Used in Chemical Synthesis:
In the chemical industry, 2-Carbomethyl-morpholine-4-carboxylic Acid Tert-Butyl Ester is used as a versatile building block for the synthesis of a wide range of chemical products. Its stability and reactivity contribute to the development of novel materials and compounds with potential applications in various fields.

InChI:InChI=1/C11H19NO5/c1-11(2,3)17-10(15)12-4-5-16-8(7-12)6-9(13)14/h8H,4-7H2,1-3H3,(H,13,14)

Upstream product

• 503601-25-0 (±)-ethyl 2-(morpholin-2-yl)acetate 
• 73933-19-4 ethyl 4-(phenylmethyl)-2-morpholineacetate 
• 766539-39-3 C₁₂H₂₁NO₅ 

Downstream Products

• 913642-78-1 (±)-tert-butyl 2-(2-hydroxyethyl)morpholine-4-carboxylate 

Relevant articles and documents

Novel anticancer compound and usage thereof

The invention provides a novel anticancer compound. The novel anticancer compound is a compound shown in chemical formula 1 in the description or pharmaceutically acceptable salt of the compound, andthe compound and the salt are active ingredients of a pharmaceutical composition for inhibiting the activity of hepatocyte growth factor receptor (c-Met) tyrosine kinase and pharmaceutical compositionfor preventing or curing excessive or abnormal proliferative diseases. The compound effectively inhibits the activity of the hepatocyte growth factor receptor tyrosine kinase, thereby being suitablefor treating the diseases with the characteristics of excessive or abnormal cell proliferation.

SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS

This invention relates to novel 2,3-dihydroimidazo[1,2-c]quinazoline compounds, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for phosphotidylinositol-3-kinase (PI3K) inhibition and treating diseases associated with phosphotidylinositol-3-kinase (PI3K) activity, in particular treating hyper-proliferative and/or angiogenesis disorders, as a sole agent or in combination with other active ingredients.