767-14-6

Basic information

• Product Name: (3R,5R)-3,5-dimethylcyclohexanol
• Synonyms: (1.alpha.,3.alpha.,5.beta.)-3,5-Dimethyl-cyclohexanol; (1alpha,3alpha,5beta)-3,5-Dimethylcyclohexanol; (3R,5R)-3,5-Dimethylcyclohexanol; cyclohexanol, 3,5-dimethyl-, (3R,5R)-
• CAS NO: 767-14-6
• Molecular Formula: C₈H₁₆O
• Molecular Weight: 128.212
• Mol File: 767-14-6.mol

Chemical Properties

• Boiling Point: 186.999°C at 760 mmHg
• Flash Point: 73.333°C
• Density: 0.894g/cm³
• Vapor Pressure: 0.18mmHg at 25°C
• Refractive Index: 1.452
• CAS DataBase Reference: (3R,5R)-3,5-dimethylcyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,5R)-3,5-dimethylcyclohexanol(767-14-6)
• EPA Substance Registry System: (3R,5R)-3,5-dimethylcyclohexanol(767-14-6)

Safety Data

• Hazardous Substances Data: 767-14-6(Hazardous Substances Data)

Usage

Uses

Used in Flavor and Fragrance Industry:
(3R,5R)-3,5-dimethylcyclohexanol is used as a fragrance ingredient and flavoring agent for its distinct minty, camphor-like odor, adding unique scents and flavors to food and cosmetic products.
Used in Chemical Synthesis:
(3R,5R)-3,5-dimethylcyclohexanol is used as a solvent and intermediate in the production of other chemicals, taking advantage of its stable and versatile chemical structure for synthesizing a wide range of compounds.
Used in Organic Chemistry Research:
(3R,5R)-3,5-dimethylcyclohexanol serves as a valuable building block in organic chemistry research, contributing to the development of new methods and understanding of chemical reactions.
Used in Pharmaceutical Synthesis:
(3R,5R)-3,5-dimethylcyclohexanol is utilized in the synthesis of pharmaceuticals and other important chemicals, playing a crucial role in the development of new drugs and medicinal compounds.

Upstream product

• 1123-09-7 3,5-dimethyl-2-cyclohexen-1-one 
• 2320-30-1 trans-3,5-dimethylcyclohexanone 

Downstream Products

• 109067-78-9 (+/-)-3.5-dinitro-benzoic acid-(3r.5t-dimethyl-cyclohexyl ester) 

Relevant articles and documents

Transfer Hydrogenation of Ketones with (1-) as the Precatalyst

The cluster 1a has been found to be an efficient precatalyst for the transfer hydrogenations of ketones and α,β-unsaturated ketones.With substrates such as (5S)-carvone , (3R)-methylcyclopentanone and (3R)-methylcyclohexanone, moderate to high diastereoselectivities were observed for reduction of the conjugated olefinic and ketonic functionalities respectively.Aromatisation of carvone to 5-isopropyl-2-methylphenol and disproportionation of cyclohex-2-en-1-one to phenol and cyclohexanone have also been found to be catalysed by 1a.Studies with radical inhibitors and other evidence suggest a radical mechanism for the transfer-hydrogenation and aromatisation reactions.In the transfer hydrogenation of cyclohex-2-en-1-one, the rate of conversion of 1a into other soluble species can be modelled accurately if autocatalysis is assumed.The time-dependent concentration profiles of cyclohex-2-en-1-one, cyclohexanone and cyclohexanol are simulated well if autocatalytic formation of an active intermediate followed by consecutive reactions leading to the formation of products is assumed.Such a model is also consistent with the proposed radical mechanism.