cas 76823-94-4, 3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER | Articles data ｜lookchem

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76823-94-4

Articles about 76823-94-4Total 6 be found

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NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR
[Problem] The present invention addresses the problem of providing a novel compound. The present invention also addresses the problem of providing an OCT3 detection agent or an OCT3 activity inhibitor, which comprises the novel compound. [Solution] A compound represented by formula (A), a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof. ????????R1-R2-R3-R4?????(A)
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Paragraph 0594-0595

(2016/08/17)

New-quanidino-thiazol compounds, their preparation, and use as intermediates of famotidine process
New 2-guanidino-thiazol compounds with the general formulas where R° represents an hydrogen atom or an alkyl group of low molecular weight, m = 2 to 7, n = 2 to 4, and being R an alkyl group of low molecular weight and that may contain from one N-alkylsilyl group, that are important intermediates for the famotidine preparation, medically used as inhibitor of the gastric secretion.
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(2008/06/13)

2-Guanidinothiazoline compounds, and process for preparing them
Novel 2-guanidinothiazoline compounds of the general formula STR1 wherein R represents a hydrogen atom or a lower alkyl group, and X represents a halogen atom, and the acid addition salts thereof; they are important intermediate compounds for preparing famotidine and thiotidine which are medicaments useful as gastric acid secretion inhibitors.
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(2008/06/13)

Histamine H2 receptor antagonists. 1. Synthesis of N-cyano and N-carbamoyl amidine derivatives and their biological activities.
A large number of N-cyano amidine derivatives were prepared as potential histamine H2 receptor antagonists and evaluated for their inhibitory action on histamine-stimulated chronotropic response of isolated right atria from guinea pigs. Several selected c
Yanagisawa,Hirata,Ishii
p. 849 - 857
(2007/10/02)

GUANIDINOTHIAZOLE COMPOUNDS, AND MEDICAL COMPOSITIONS CONTAINING THEM
Novel guanidinothiazole compounds of the general formula STR1 wherein R represents a hydrogen atom or a lower alkyl group, Y represents a sulfur atom or a methylene group, m and n each represents an integer of 1-3, A represents the group shown by STR2 (wh
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(2008/06/13)

GUANIDINOTHIAZOLE COMPOUNDS, PROCESS FOR PREPARATION AND GASTRIC INHIBITING COMPOSITIONS CONTAINING THEM
Novel guanidinothiazole compounds of the general formula STR1 wherein R represents a hydrogen atom or a lower alkyl group, R. sub.1 represents an amino group, a lower alkyl group, a halogeno lower alkyl group, a substituted-or unsubstituted-aryl group, a
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(2008/06/13)

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Chemical Properties

Boiling Point: 416.8°C at 760 mmHg
Flash Point:205.9°C
Density: 1.49g/cm³
Vapor Pressure: 3.72E-07mmHg at 25°C
PKA: 8.53±0.70(Predicted)
PSA: 161.41000
LogP: 2.66820

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