76823-94-4

Basic information

• Product Name: 3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER
• Synonyms: 3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER;3-(((2-((Aminoimi-nomethyl)amino)-4-thiazolyl)methyl)thio)propanimidic acid;3-(((2-Guanidino-4-thiazolyl)methyl)thio)propanimidic acid methyl ester;3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-propanimidic aci;3-[[[2-[(AMinoiMinoMethyl)aMino]-4-thiazolyl]Methyl]thio]propaniMidic Acid Methyl Ester;DediaMinosulfonyl HydroxyMethyl FaMotidine
• CAS NO: 76823-94-4
• Molecular Formula: C₉H₁₅N₅OS₂
• Molecular Weight: 273.38
• Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 76823-94-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 416.8°C at 760 mmHg
• Flash Point: 205.9°C
• Appearance: /
• Density: 1.49g/cm³
• Vapor Pressure: 3.72E-07mmHg at 25°C
• Refractive Index: 1.69
• PKA: 8.53±0.70(Predicted)
• CAS DataBase Reference: 3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER(76823-94-4)
• EPA Substance Registry System: 3-(((2-GUANIDINO-4-THIAZOLYL)METHYL)THIO)PROPANIMIDC ACID METHYL ESTER(76823-94-4)

Safety Data

• Hazardous Substances Data: 76823-94-4(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

Dediaminosulfonyl Hydroxymethyl Famotidine is an impurity of Famotidine (F102250), a histamine H2-receptor antagonist.

InChI:InChI=1/C9H15N5OS2/c1-15-7(10)2-3-16-4-6-5-17-9(13-6)14-8(11)12/h5,10H,2-4H2,1H3,(H4,11,12,13,14)

Upstream product

• 76823-92-2 3-<<<2-(S-methylisithioureido)-4-thiazolyl>methyl>thio>propionitrile hydroiodide 
• 76823-90-0 3-<<<2-(3-benzoylthioureido)-4-thiazolyl>methyl>thio>propionitrile 
• 76823-91-1 3-<<(2-thioureido-4-thiazolyl)methyl>thio>propionitrile 
• 76823-89-7 3-(2-aminothiazol-4-yl-methylthio)propionitrile 
• 67-56-1 methanol 
• 76823-93-3 N''-[4-[[(2-cyanoethyl)thio]methyl]-2-thiazolyl]-guanidine 

Downstream Products

• 76823-88-6 3-[(2-guanidinothiazol-4-yl)methylthio]propionamidoxime 
• 90237-03-9 3-<<<2-<(diaminomethylene)amino>-4-thiazolyl>methyl>sulfinyl>-N²-sulfamoylpropionamidine 
• 76824-17-4 <3-<<<2-<(diaminomethylene)amino>-4-thiazolyl>methyl>thio>propionyl>sulfamide hydrochloride 
• 107880-74-0 3-<<<2-<(diaminomethylene)amino>-4-thiazolyl>methyl>thio>propionic acid 
• 76824-05-0 3-<<<2-<(diaminomethylene)amino>-4-thiazolyl>methyl>thio>-N²-(phenylsulfonyl)propionamidrazone 
• 89268-62-2 3,5-bis<2-<<<2-<(diaminomethylene)amino>-4-thiazolyl>methyl>thio>ethyl>-4H-1,2,4,6-thiatriazine 1,1-dioxide 
• 76824-35-6 famotidine 
• 76824-16-3 3-<2-(diaminomethyleneamino)-4-thiazolylmethylthio>-propionamide 
• 76823-97-7 3-<<<2-<(diaminomethylene)amino>-4-thiazolyl>methyl>thio>-N'-cyanopropionamidine 
• 77219-55-7 3-<<<2-<(diaminomethylene)amino>-4-thiazolyl>methyl>thio>-N²-(phenylsulfonyl)propionamidine 

Relevant articles and documents

NOVEL COMPOUND, ORGANIC CATION TRANSPORTER 3 DETECTION AGENT, AND ORGANIC CATION TRANSPORTER 3 ACTIVITY INHIBITOR

[Problem] The present invention addresses the problem of providing a novel compound. The present invention also addresses the problem of providing an OCT3 detection agent or an OCT3 activity inhibitor, which comprises the novel compound. [Solution] A compound represented by formula (A), a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable solvate thereof. ????????R1-R2-R3-R4?????(A)

2-Guanidinothiazoline compounds, and process for preparing them

Novel 2-guanidinothiazoline compounds of the general formula STR1 wherein R represents a hydrogen atom or a lower alkyl group, and X represents a halogen atom, and the acid addition salts thereof; they are important intermediate compounds for preparing famotidine and thiotidine which are medicaments useful as gastric acid secretion inhibitors.

GUANIDINOTHIAZOLE COMPOUNDS, AND MEDICAL COMPOSITIONS CONTAINING THEM

Novel guanidinothiazole compounds of the general formula STR1 wherein R represents a hydrogen atom or a lower alkyl group, Y represents a sulfur atom or a methylene group, m and n each represents an integer of 1-3, A represents the group shown by STR2 (wh