77199-09-8

Basic information

• Product Name: 5-bromo-2-pyridinecarboxylic acid ethyl ester
• Synonyms: Ethyl 5-bromo-2-pyridinecarboxylate;Ethyl 5-bromopicolinate;2-Pyridinecarboxylic acid, 5-broMo-, ethyl ester
• CAS NO: 77199-09-8
• Molecular Formula: C₈H₈BrNO₂
• Molecular Weight: 230.07
• Product Categories: API intermediates;Heterocycle-Pyridine series
• Mol File: 77199-09-8.mol

Chemical Properties

• Melting Point: 63-64℃
• Boiling Point: 304℃
• Flash Point: 138℃
• Appearance: /
• Density: 1.501
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -0.53±0.10(Predicted)
• CAS DataBase Reference: 5-bromo-2-pyridinecarboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-pyridinecarboxylic acid ethyl ester(77199-09-8)
• EPA Substance Registry System: 5-bromo-2-pyridinecarboxylic acid ethyl ester(77199-09-8)

Safety Data

• Hazardous Substances Data: 77199-09-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-bromo-2-pyridinecarboxylic acid ethyl ester is utilized as a key building block in the synthesis of various pharmaceuticals. Its unique structure and reactivity make it a valuable component in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 5-bromo-2-pyridinecarboxylic acid ethyl ester serves as an essential intermediate for the preparation of agrochemicals. Its incorporation into the molecular structures of these compounds can enhance their effectiveness in pest control and crop protection.
Used in Organic Synthesis:
5-bromo-2-pyridinecarboxylic acid ethyl ester is employed as a versatile reagent in organic synthesis. Its ability to participate in a range of chemical reactions, such as nucleophilic substitution, electrophilic aromatic substitution, and cross-coupling reactions, makes it a valuable tool for the preparation of heterocyclic compounds and other organic intermediates.
Used in Fine Chemicals Production:
5-bromo-2-pyridinecarboxylic acid ethyl ester is also used in the production of fine chemicals, where its unique properties and reactivity contribute to the synthesis of high-value specialty chemicals for various applications, including fragrances, dyes, and other performance chemicals.
Used in Chemical Research and Development:
5-bromo-2-pyridinecarboxylic acid ethyl ester plays a crucial role in the field of chemical research and development. Its unique properties and versatile applications make it an important compound for exploring new chemical reactions, developing novel synthetic methods, and discovering new chemical entities with potential applications in various industries.

Upstream product

• 30766-11-1 5-bromoisonicotinic acid 
• 64-17-5 ethanol 
• 624-28-2 2,5-dibromopyridine 
• 201230-82-2 carbon monoxide 
• 3430-13-5 5-bromo-2-methylpyridine 
• 137178-88-2 5-bromopyridine-2-carbonyl chloride 
• 29682-15-3 methyl 5-bromopicolinate 
• 109-94-4 formic acid ethyl ester 
• 667-27-6 Ethyl bromodifluoroacetate 

Downstream Products

• 77199-10-1 α-<5-bromopicoloyl>-γ-butyrolactone 
• 1416733-02-2 2-(5-bromopyridin-2-yl)-1-(2,4-difluorophenyl)-2,2-difluoro-1-(pyrimidin-5-yl)ethanol 
• 1581280-31-0 1-(2,4-difluorophenyl)-2,2-difluoro-2-(5-((4-fluorophenyl)ethynyl)pyridin-2-yl)-1-(pyrimidin-5-yl)ethanol 
• 1581280-33-2 C₂₄H₁₄F₇N₃O₂ 
• 30766-11-1 5-bromoisonicotinic acid 
• 75754-04-0 5-phenyl-pyridine-2-carboxylic acid 
• 1225956-67-1 5-(p-tolyl)picolinic acid 
• 536-69-6 Fusaric acid 
• 741709-57-9 ethyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-2-carboxylate 
• 65117-74-0 ethyl 5-phenylpicolinate 
• 1269028-89-8 ethyl 5-(benzyloxy)-6-ethyl-1-methyl-3-(2,2,2-trifluoroethoxy)-1H-pyrrolo[3,2-b]pyridine-2-carboxylate 
• 1269028-97-8 6-ethyl-1-methyl-5-[(phenylcarbonyl)amino]-3-(2,2,2-trifluoroethoxy)-1H-pyrrolo[3,2-b]pyridine-2-carboxylic acid 
• 1269028-88-7 ethyl 5-(benzyloxy)-6-ethyl-3-hydroxy-1-methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylate 
• 1269028-86-5 ethyl 6-(benzyloxy)-3-[(2-ethoxy-2-oxoethyl)(methyl)amino]-5-ethylpyridine-2-carboxylate 

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