77542-16-6

Basic information

• Product Name: 4,4-dimethoxypiperidine
• Synonyms: 4,4-Dimethoxypiperidine; piperidine, 4,4-dimethoxy-
• CAS NO: 77542-16-6
• Molecular Formula: C₇H₁₅NO₂*ClH
• Molecular Weight: 145.1995
• Mol File: 77542-16-6.mol

Chemical Properties

• Boiling Point: 177.3°C at 760 mmHg
• Flash Point: 65.3°C
• Density: 0.99g/cm³
• Vapor Pressure: 1.04mmHg at 25°C
• Refractive Index: 1.452
• CAS DataBase Reference: 4,4-dimethoxypiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4-dimethoxypiperidine(77542-16-6)
• EPA Substance Registry System: 4,4-dimethoxypiperidine(77542-16-6)

Safety Data

• Hazardous Substances Data: 77542-16-6(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 40064-34-4 4-piperidone monohydrochloride monohydrate 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 959976-99-9 C₂₀H₃₀N₂O₄ 
• 1097917-15-1 N-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)-piperidin-1-yl]phenyl}-N′-[2-(propane-2-sulfonyl)phenyl]-1,3,5-triazine-2,4-diamine 
• 1097917-68-4 1-[3-methoxy-4-({4-[2-(propane-2-sulfonyl)anilino]-1,3,5-triazin-2-yl}amino)phenyl]piperidin-4-one 
• 1613244-43-1 2-(4,4-dimethoxypiperidin-1-yl)-1-(phenanthridin-5(6H)-yl)propan-1-one 

Relevant articles and documents

Double axial chirality promoted asymmetric [2,3] Stevens rearrangement of N-cinnamyl l-alanine amide-derived ammonium ylides

The base-induced asymmetric [2,3] Stevens rearrangement of N-cinnamyl tetraalkylammonium ylides derived from l-alanine amides proceeds via a double axially chiral intermediate to afford the corresponding α-substituted alanine derivatives with high enantio- and diastereoselectivities. the Partner Organisations 2014.

JAK INHIBITOR

A JAK inhibitor comprising, as an active ingredient, a nitrogen-containing heterocyclic compound represented by formula (I) {wherein W represents a nitrogen atom or -CH-; X represents -C (=O) - or -CHR4- (wherein R4 represents a hydrogen atom, or the like); R1 represents the formula described below [wherein Q1 represents-CR8-(wherein R8 represents a hydrogen atom, substituted or unsubstituted lower alkyl, or the like); Q2 represents -NR15- (wherein R15 represents a hydrogen atom, substituted or unsubstituted lower alkyl, or the like); and R5 and R6 may be the same or different and each represents a hydrogen atom, halogen, carboxy, substituted or unsubstituted lower alkyl, or the like], or the like; and R2 and R3 may be the same or different and each represents a hydrogen atom, halogen, substituted or unsubstituted lower alkyl, or the like} or a pharmaceutically acceptable salt thereof.