- Synthesis of 1-(2-ethoxyethyl)-4-hydroxy-4-[2-(1-hydroxycyclohexyl)ethynyl] -piperidine and heterocyclization under the conditions of hydration
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The reaction of 1-(2-ethoxyethyl)piperidin-4-one with ethynylcyclohexanol led to the synthesis of a glycol, the hydration of which gave a mixture of spirocyclic compounds with a carbonyl group at various positions in the furan ring. 2005 Springer Science+
- Bazhykova,Poplavskaya,Praliev
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- Synthesis and Transformations of Novel Acetylene Glycols Derived from N-Substituted Piperidin-4-ones
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Abstract: With the aim to prepare asymmetric acetylenic γ-glycols, the reactions of 1-(2-ethoxyethyl)piperidin-4-one with propargyl alcohol were studied and the reaction conditions were optimized to reach satisfactory yields of the target glycols. Some tr
- Bazhykova
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p. 203 - 211
(2021/04/02)
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- NOVEL BIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMER
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Provided is a compound that can be used for a resin for a resist having excellent sensitivity, resolution, and etching resistance, or the like, by a compound represented by the following formula (1): (wherein R1 represents a hydrogen atom or a methyl group, R2 represents an aliphatic hydrocarbon group having 1 to 6 carbon atoms, m represents an integer of 0 to 5, and n represents an integer of 0 to 4).
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Paragraph 0050
(2020/12/25)
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- NEW BIFUNCTIONAL (METH)ACRYLATE COMPOUND AND POLYMER
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Provided is a compound that can be used for a resin for a resist having excellent sensitivity, resolution, and etching resistance, or the like, by a compound represented by the following formula (1): (wherein R1 represents a hydrogen atom or a
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Paragraph 0058-0061
(2020/12/25)
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- Rhodium-Catalyzed Arylative Transformations of Propargylic Diols: Dual Role of the Rhodium Catalyst
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Controllable synthesis of a variety of allenic alcohols and 2,5-dihydrofurans by rhodium(I)-catalyzed arylative transformations of propargylic diols is reported. The hydroxorhodium catalyst was found to play dual role: it catalyzed the arylation/dehydroxylation reaction of propargylic diols to afford allenic alcohols, and besides, it could convert to a cationic rhodium species in situ, which catalyzed the intramolecular hydroalkoxylation of allenic alcohols to form dihydrofurans. Remarkably, generation of the cationic rhodium species is dependent on the arylboron reagent used. Thus, the controllable synthesis is achieved by simply changing the arylboron reagent. (Figure presented.).
- Xing, Junhao,Zhu, Yong,Lin, Xiao,Liu, Na,Shen, Yue,Lu, Tao,Dou, Xiaowei
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supporting information
p. 1595 - 1599
(2018/03/01)
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- Flash chemistry using trichlorovinyllithium: Switching the reaction pathways by high-resolution reaction time control
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High-resolution reaction time control in flow microreactors enables the reaction-pathway switching of trichlorovinyllithium generated by the H/Li exchange of trichloroethene. The method was successfully app lied to the synthesis of 1,1,2-trichloroalkenes,
- Nagaki, Aiichiro,Takahashi, Yusuke,Henseler, Andrea,Matsuo, Chika,Yoshida, Jun-Ichi
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supporting information
p. 214 - 216
(2015/03/05)
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- Lithiation of 1,2-dichloroethene in flow microreactors: Versatile synthesis of alkenes and alkynes by precise residence-time control
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It′s all about the timing: Precise control of the residence time (tRx; see picture) of reactive intermediates in flow microreactors enables the reaction pathway of lithiated 1,2-dichloroethene to be switched to produce either alkenes or alkynes. This method also allows versatile syntheses of asymmetric disubstituted dichloroalkenes and alkynes. Copyright
- Nagaki, Aiichiro,Matsuo, Chika,Kim, Songhee,Saito, Kodai,Miyazaki, Atsuo,Yoshida, Jun-Ichi
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supporting information; experimental part
p. 3245 - 3248
(2012/05/31)
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- A novel iodine-promoted tandem cyclization: An efficient synthesis of substituted 3,4-diiodoheterocyclic compounds
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(Figure Presented) Iodine sets allenes ringing: A novel iodine-promoted tandem cyclization reaction of but-2-yne-1,4-diol and 4aminobut-2-yn-l-ol derivatives leading to substituted 3, 4-diiodoheterocyclic compounds has been developed (see scheme). In this
- Ji, Ke-Gong,Zhu, Hai-Tao,Yang, Fang,Shu, Xing-Zhong,Zhao, Shu-Chun,Liu, Xue-Yuan,Shaukat, Ali,Liang, Yong-Min
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supporting information; experimental part
p. 6151 - 6154
(2010/07/05)
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- Synthesis of five- and six-membered dihalogenated heterocyclic compounds by electrophile-triggered cyclization
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Highly substituted dihalogenated dihydrofurans, dihydropyrroles, and dihydro-2H-pyrans bearing alkyl, vinyl, aryl, and heteroaryl moieties can be prepared in good to excellent yields (up to 99%) by allowing 1,4-butyne-diol, 4-aminobut-2-yn-1-ol, and pent-2-yne-1,5-diol derivatives to react with different electrophiles (I2, IBr, and ICl) at room temperature. Both halogen atoms generated from electrophiles were used effectively. The resulting halides can be further exploited by using palladium-catalyzed coupling reactions. The presence of trace amount of water is essential for this electrophilic cyclization.
- Ji, Ke-Gong,Zhu, Hai-Tao,Yang, Fang,Shaukat, Ali,Xia, Xiao-Feng,Yang, Yan-Fang,Liu, Xue-Yuan,Liang, Yong-Min
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supporting information; experimental part
p. 5670 - 5678
(2010/11/05)
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- Double dehydro-diels-alder reactions of 1,5-dien-3-ynes
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A study was conducted to demonstrate double dehydro-diels-alder reactions of 1,5-dien-3-ynes. It was demonstrated that the reaction proceeded through two concerted cycloadditions, the first of which was proposed to be reversible. Detailed analysis reveale
- Fallon, Thomas,Robinson, Diane E.J.E.,Willis, Anthony C.,Paddon-Row, Michael N.,Sherburn, Michael S.
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supporting information; experimental part
p. 760 - 765
(2010/05/18)
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- Regiocontrolled Formation of 4,5-Dihydro-3(2H)-furanones from 2-Butyne-1,4-diol Derivatives. Synthesis of Bullatenone and Geiparvarin
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Two new methods for selective hydration of 1,1,4-trisubstituted 2-butyne-1,4-diols (1) to give 4,5-dihydro-3(2H)-furanone derivatives are reported.The first involves selective monoacetylation of the less hindered hydroxyl group of 1 followed by Ag(I)-cata
- Saimoto, Hiroyuki,Hiyama, Tamejiro,Nozaki, Hitosi
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p. 3078 - 3087
(2007/10/02)
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- Applications of Phase Transfer Catalysis, 24. - Note on the Acceleration of Reactions between Alkynes and Carbonyl Compounds
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Reactions between the title compounds in toluene/15percent aqueous sodium hydroxide are accelerated by the presence of N(C4H9)Br.
- Dehmlow, Eckehard V.,Shamout, Abdul Rahman
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p. 1750 - 1752
(2007/10/02)
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