782504-66-9 Usage
Uses
Used in Organic Synthesis:
2-(3-Trifluoromethyl-benzyl)-piperidine hydrochloride is used as a building block for the synthesis of various organic compounds. Its unique structure allows for the creation of a wide range of molecules with potential applications in different fields.
Used in Pharmaceutical Research:
2-(3-Trifluoromethyl-benzyl)-piperidine hydrochloride is used as a research tool in the development of new pharmaceuticals. Its properties make it a valuable asset in the search for novel drug candidates.
Used in Neurotransmission Studies:
2-(3-Trifluoromethyl-benzyl)-piperidine hydrochloride is used as a potent and selective dopamine D2 receptor antagonist. This makes it a valuable tool in the study of dopamine-mediated neurotransmission, which is crucial for understanding the mechanisms behind various neurological and psychiatric disorders.
Used in Treatment of Neurological and Psychiatric Disorders:
Although further research is needed, 2-(3-Trifluoromethyl-benzyl)-piperidine hydrochloride has potential applications in the treatment of various neurological and psychiatric disorders. Its role as a dopamine D2 receptor antagonist suggests that it could be used to manage conditions related to dopamine dysregulation.
Check Digit Verification of cas no
The CAS Registry Mumber 782504-66-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,8,2,5,0 and 4 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 782504-66:
(8*7)+(7*8)+(6*2)+(5*5)+(4*0)+(3*4)+(2*6)+(1*6)=179
179 % 10 = 9
So 782504-66-9 is a valid CAS Registry Number.
InChI:InChI=1/C13H16F3N.ClH/c14-13(15,16)11-5-3-4-10(8-11)9-12-6-1-2-7-17-12;/h3-5,8,12,17H,1-2,6-7,9H2;1H
782504-66-9Relevant articles and documents
Convenient, benign and scalable synthesis of 2- and 4-substituted benzylpiperidines
Agai, Bela,Proszenyak, Agnes,Tarkanyi, Gabor,Vida, Laszlo,Faigl, Ferenc
, p. 3623 - 3632 (2007/10/03)
A short, scalable and environmentally benign synthesis of 2- and 4-substituted benzylpiperidines has been developed. The method is based on the temperature-programmed consecutive deoxygenation and heteroaromatic ring saturation of aryl(pyridin-2-yl)- and aryl(pyridin-4-yl)methanols and aryl(pyridin-4-yl)methanones in the presence of Pd/C catalyst. The crucial roles of the temperature, the acidity and the substrate structure in the change of selectivity have been demonstrated by isolation of several substituted aryl(piperidine)methanols. The carbinols and ketones were prepared from commercially available pyridinecarbaldehydes or 4-cyanopyridine and substituted bromobenzenes via organometallic intermediates. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.
