- A Series of 2,4(1H,3H)-Quinazolinedione derivatives: Synthesis and biological evaluation as potential anticancer agents
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A series of 6,7-disubstituted-3-{2-[4-(substituted)piperazin-1-yl]-2-oxoethyl}quinazoline- 2,4(1H,3H)-dione derivatives (7-34) were synthesized and their structures were elucidated on the basis of analytical and spectral (UV, IR, 1H-NMR, 1
- Akgun, Hulya,Yilmaz, Demet Us,Atalay, Rengul Cetin,Gozen, Damla
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- A series of 2,4(1H,3H)-quinazolinedione derivatives: Synthesis and biological evaluation as potential anticancer agents
-
A series of 6,7-disubstituted-3-{2-[4-(substituted)piperazin-1-yl]-2-oxoethyl}quinazoline-2,4(1H,3H)-dione derivatives (7-34) were synthesized and their structures were elucidated on the basis of analytical and spectral (UV, IR, 1H-NMR, 13
- Akgun, Hulya,Yilmaz, Demet Us,Atalay, Rengul Cetin,Gozen, Damla
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- Reactions of o-Aminonitriles with Isocyanates. 2. A Facile Synthesis of Imidazoquinazoline-2,5-(3H,6H)dione
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Anthranilonitrile reacts with ethyl isocyanatoacetate to form 2-(3-ethoxycarbonylmethylureido)benzonitrile (3b) which, upon heating, or treatment with a base, undergoes a double cyclization to yield imidazo-quinazoline-2,5-(3H,6H)dione (5) in excel
- Papadopoulos, Eleftherios Paul
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p. 515 - 518
(2007/10/02)
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