78754-95-7Relevant articles and documents
A Series of 2,4(1H,3H)-Quinazolinedione derivatives: Synthesis and biological evaluation as potential anticancer agents
Akgun, Hulya,Yilmaz, Demet Us,Atalay, Rengul Cetin,Gozen, Damla
, p. 64 - 76 (2016)
A series of 6,7-disubstituted-3-{2-[4-(substituted)piperazin-1-yl]-2-oxoethyl}quinazoline- 2,4(1H,3H)-dione derivatives (7-34) were synthesized and their structures were elucidated on the basis of analytical and spectral (UV, IR, 1H-NMR, 1
Reactions of o-Aminonitriles with Isocyanates. 2. A Facile Synthesis of Imidazoquinazoline-2,5-(3H,6H)dione
Papadopoulos, Eleftherios Paul
, p. 515 - 518 (2007/10/02)
Anthranilonitrile reacts with ethyl isocyanatoacetate to form 2-(3-ethoxycarbonylmethylureido)benzonitrile (3b) which, upon heating, or treatment with a base, undergoes a double cyclization to yield imidazo-quinazoline-2,5-(3H,6H)dione (5) in excel