Reaction of 4-Chloro-3-nitrocoumarin with Glycine and Alanine, and the Synthesis of 1-Benzopyranopyrimidine-3,5-dione
A considerable improvement of the yields obtained in substitution of halogens in 4-chloro-3-nitrocoumarin by amino acid or amino acid ester residues was achieved over literature claims.Electrochemical reduction of the nitro group in these products brought about a ring closure leading to benzopyranopyrimidinones, which are obtained in excellent yields.
Stunic', Z.,Trkovnik, M.,Lac'an, M.,Jankovic',R.
p. 511 - 513
(2007/10/02)
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