78795-04-7Relevant academic research and scientific papers
Reaction of 4-Chloro-3-nitrocoumarin with Glycine and Alanine, and the Synthesis of 1-Benzopyranopyrimidine-3,5-dione
Stunic', Z.,Trkovnik, M.,Lac'an, M.,Jankovic',R.
, p. 511 - 513 (2007/10/02)
A considerable improvement of the yields obtained in substitution of halogens in 4-chloro-3-nitrocoumarin by amino acid or amino acid ester residues was achieved over literature claims.Electrochemical reduction of the nitro group in these products brought about a ring closure leading to benzopyranopyrimidinones, which are obtained in excellent yields.
