Tricyclic oxazolo[2,3-f]purinediones: Potency as adenosine receptor ligands and anticonvulsants
A series of tricyclic mono- or disubstituted oxazolo[2,3-f]purinediones was synthesized and evaluated for their adenosine receptor affinity and anticonvulsant activity. Mainly selective adenosine A2A receptor antagonists were identified. A 7-be
Drabczyńska, Anna,Müller, Christa E.,Schumacher, Britta,Hinz, Sonja,Karolak-Wojciechowska, Janina,Michalak, Barbara,P?kala, Elzbieta,Kie?-Kononowicz, Katarzyna
Reaction between 8-chlorotheophylline and epoxides. A simple preparation of oxazolido[2,3-f]purines
The reaction of epoxides with 8-chlorotheophylline (1) produced the corresponding oxazolido[2,3-f]purines via nucleophilic addition and intramolecular nucleophilic substitution.
Jin,Nishikubo
p. 6307 - 6308
(2007/10/02)
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