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Tert-butyl 4-Methylideneazepane-1-carboxylate is a carboxylate ester with the molecular formula C12H21NO2. It is a chemical compound commonly used in organic synthesis and pharmaceutical research. Known for its ability to act as a reagent in the preparation of various organic molecules, particularly in the formation of cyclic structures, its tert-butyl group provides steric hindrance, which can influence the reactivity and selectivity of chemical reactions where it is involved. Tert-butyl 4-Methylideneazepane-1-carboxylate is considered a valuable building block in the creation of diverse chemical compounds and plays an important role in the development of new pharmaceutical drugs and materials.

790705-08-7

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790705-08-7 Usage

Uses

Used in Organic Synthesis:
Tert-butyl 4-Methylideneazepane-1-carboxylate is used as a reagent for the preparation of various organic molecules, particularly in the formation of cyclic structures. Its steric hindrance provided by the tert-butyl group influences the reactivity and selectivity of chemical reactions, making it a valuable building block in the creation of diverse chemical compounds.
Used in Pharmaceutical Research:
Tert-butyl 4-Methylideneazepane-1-carboxylate is used as a key intermediate in the development of new pharmaceutical drugs and materials. Its unique properties and reactivity make it a promising candidate for the synthesis of novel therapeutic agents and drug delivery systems.

Check Digit Verification of cas no

The CAS Registry Mumber 790705-08-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,9,0,7,0 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 790705-08:
(8*7)+(7*9)+(6*0)+(5*7)+(4*0)+(3*5)+(2*0)+(1*8)=177
177 % 10 = 7
So 790705-08-7 is a valid CAS Registry Number.

790705-08-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 4-methylideneazepane-1-carboxylate

1.2 Other means of identification

Product number -
Other names tert-Butyl 4-methyleneazepane-1-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:790705-08-7 SDS

790705-08-7Downstream Products

790705-08-7Relevant articles and documents

Site-Specific Alkene Hydromethylation via Protonolysis of Titanacyclobutanes

Bartfield, Noah M.,Frederich, James H.,Law, James A.

supporting information, p. 14360 - 14364 (2021/05/27)

Methyl groups are ubiquitous in biologically active molecules. Thus, new tactics to introduce this alkyl fragment into polyfunctional structures are of significant interest. With this goal in mind, a direct method for the Markovnikov hydromethylation of alkenes is reported. This method exploits the degenerate metathesis reaction between the titanium methylidene unveiled from Cp2Ti(μ-Cl)(μ-CH2)AlMe2 (Tebbe's reagent) and unactivated alkenes. Protonolysis of the resulting titanacyclobutanes in situ effects hydromethylation in a chemo-, regio-, and site-selective manner. The broad utility of this method is demonstrated across a series of mono- and di-substituted alkenes containing pendant alcohols, ethers, amides, carbamates, and basic amines.

INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF

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Paragraph 00529; 00530, (2021/08/13)

Compounds and methods for their preparation and use as therapeutic or prophylactic agents, for example for treatment of cancer, bacterial or viral diseases by targeting Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1).

Oxazolidinone-quinolone hybrid antibiotics

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Page/Page column 25, (2015/11/10)

The present invention relates to compounds of the Formula (I) that are useful antimicrobial agents and effective against a variety of multi-drug resistant bacteria:

Synthesis of functionalized 2-isoxazolines as three-dimensional fragments for fragment-based drug discovery

Tran, Ngoc Chau,Dhondt, Heleen,Flipo, Marion,Deprez, Benoit,Willand, Nicolas

supporting information, p. 4119 - 4123 (2015/08/03)

Abstract The design of new sp3 and spiro-enriched fragments has been achieved from 1,3-dipolar cycloaddition between alkenes and chloro-oximes. The selection of reagents was performed to afford a panel of 2-isoxazoline-containing fragments that show desirable three dimensional (3D) characteristics to allow the probing of biologically-relevant chemical space. Principal moments of inertia (PMI) were calculated to evaluate the 3D diversity. The resulting 3D fragments with suitable physicochemical properties, especially a good solubility, will be used to improve the hit rate of our fragment-based screening.

NOVEL KINASE INHIBITORS

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Paragraph 0211, (2014/05/07)

The present invention provides derivatives of thiazolylamino-substituted heterocycles. These compounds are inhibitors of kinases, including compounds that show antiproliferative activity against cells, including against tumor cells, and are useful in the treatment of diseases including cancer.

7-(Piperazine-1-Ymethyl)-1H-Indole-2-Carboxylic Acid (Phenyl)-Amide Derivatives and Allied Compounds as P38 Map Kinase Inhibitors for the Treatment of Respiratory Diseases

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Page/Page column 50, (2011/11/12)

The present invention provides compounds according to general formula (I) which are proposed for the treatment of respiratory complaints, particularly asthma and COPD.

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