791137-20-7Relevant articles and documents
PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF
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Paragraph 1099; 1097, (2018/05/24)
The present invention provides compounds, compositions thereof, and methods of using the same.
Thiazolylmethyl ortho-substituted phenyl glucoside library as novel C-aryl glucoside SGLT2 inhibitors
Lee, Suk Ho,Kim, Min Ju,Lee, Sung-Han,Kim, Jeongmin,Park, Hyun-Ju,Lee, Jinhwa
experimental part, p. 2662 - 2675 (2011/07/08)
In order to investigate SAR regarding proximal phenyl ring in novel C-aryl glucoside SGLT2 inhibitors containing a thiazole motif, a series of chemical modifications on proximal phenyl ring was conducted. During a series of lead optimization efforts, orth
NOVEL C-ARYL GLUCOSIDE SGLT2 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME
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Page/Page column 116, (2010/12/31)
A novel C-aryl glucoside compound, or a pharmaceutically acceptable salt or a prodrug thereof having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney; and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly, diabetes, are provided.
An improved synthesis of 1-acetyl-1H-indol-3-yl acetates
Rodriguez-Dominguez, Juan C.,Balbuzano-Deus, Alexander,Lopez-Lopez, Miguel A.,Kirsch, Gilbert
, p. 273 - 275 (2008/03/14)
(Chemical Equation Presented) An efficient two steps procedure for the synthesis of 1-acetyl-1H-indol-3-yl acetates, starting from 2-chlorobenzoic acids, was developed and in general, moderate to good yields were obtained.