79239-83-1Relevant articles and documents
Preparation method of 2,4-dichlorophenoxyacetic acid and salt thereof
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Paragraph 0119; 0120, (2019/01/06)
The invention provides a preparation method of 2,4-dichlorophenoxyacetic acid and a salt thereof, wherein the preparation method includes the following steps: S1) carrying out a reaction of phenol andchloracetic ester under alkaline conditions to obtain phenoxyacetic ester; S2) carrying out selective chlorination reaction of the phenoxyacetic ester with a chlorinating agent under the action of acatalyst A and a catalyst B to obtain 2,4-dichlorophenoxyacetic ester, wherein the catalyst A is Lewis acid, and the catalyst B is C5-22 thioethers, thiazoles, isothiazoles and thiophenes or halogenated derivatives thereof; and S3) carrying out hydrolysis reaction of 2,4-dichlorophenoxyacetic ester under acidic conditions to obtain 2,4-dichlorophenoxyacetic acid; or after 2,4-dichlorophenoxyaceticester is obtained, carrying out an alkaline hydrolysis reaction with an alkaline compound to obtain 2,4-dichlorophenoxyacetate. The production and use of 2,4-dichlorophenol with unpleasant odor are avoided, the production of dioxins is eliminated, the yield of products is improved, and the output of three wastes is greatly reduced.
A rapid microwave-assisted esterification utilizing the Mukaiyama supported reagent
Donati, Donato,Morelli, Costanza,Taddei, Maurizio
, p. 2817 - 2819 (2007/10/03)
Microwave heating was applied to a modified Mukaiyama reagent supported on a PS-DVB resin to develop a rapid and efficient protocol for the solution-phase synthesis of esters and lactones starting from alcohol and carboxylic acids. The products were obtained in high purity (NMR analysis) after a simple resin filtration.
