Welcome to LookChem.com Sign In|Join Free
  • or

108-95-2

Post Buying Request

108-95-2 Suppliers

Recommended suppliersmore

Product FOB Price Min.Order Supply Ability Supplier
Phenol
Cas No: 108-95-2
USD $ 1.0-2.0 / Metric Ton 1 Metric Ton 5000 Metric Ton/Day HuBei Ipure Biotech CO.,ltd Contact Supplier
Phenol CAS NO.108-95-2
Cas No: 108-95-2
USD $ 1200.0-1300.0 / Metric Ton 5 Metric Ton 10 Metric Ton/Month Hebei yanxi chemical co.,LTD. Contact Supplier
Factory supply Phenol CAS NO.108-95-2 best price
Cas No: 108-95-2
No Data 5 Metric Ton 3500 Metric Ton/Month Shandong Haohuashengna Bio-technology Co., Ltd Contact Supplier
High quality with low price 99% phenol
Cas No: 108-95-2
No Data 100 Kilogram 300 Metric Ton/Day Lonwin Chemical Group Limited Contact Supplier
Phenol
Cas No: 108-95-2
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Hangzhou Dayangchem Co., Ltd. Contact Supplier
Phenol
Cas No: 108-95-2
No Data 1 Gram 20 Metric Ton/Month Henan Allgreen Chemical Co.,Ltd Contact Supplier
Phenol CAS#108-95-2
Cas No: 108-95-2
USD $ 1800.0-1800.0 / Kilogram 25 Kilogram 20 Metric Ton/Month ORCHID CHEMICAL SUPPLIES LTD Contact Supplier
Coking phenol
Cas No: 108-95-2
USD $ 1.0-1.0 / Kilogram 1 Kilogram 1000 Metric Ton/Year Henan Sinotech Import&Export Corporation Contact Supplier
Phenol
Cas No: 108-95-2
No Data 1 Kilogram 300 Kilogram/Month HENAN SUNLAKE ENTERPRISE CORPORATION Contact Supplier
High quality Phenol CAS NO.108-95-2
Cas No: 108-95-2
USD $ 1000.0-1500.0 / Kilogram 1 Kilogram 100 Metric Ton/Month Crovell Biotech (Hebei) Co., Ltd. Contact Supplier

108-95-2 Usage

Toxicity

Phenol is highly corrosive and toxic. It mainly affects the central nervous system. The oral lethal dose for adults is 1 g. It can be irritating, numbing or necrotizing to the skin. It is toxic to skin contact, swallowing or inhalation of phenol. Misuse of a small amount of phenol can cause nausea, vomiting, shock, coma and even death in case of respiratory failure. Very few amounts are used as a preservative, so that adverse reactions are rarely found.
Due to its high toxicity, it has been replaced by more effective and less toxic phenolic derivatives.

Chemical Properties

Phenol, C6H5OH, also known as carbolic acid and phenylic acid, is a white poisonous crystalline solid that melts at 43 °C (110 OF) and boils at 182°C (360 OF). Phenol has a sharp burning taste,a distinctive odor, and it irritates tissue. It is toxic not only by ingestion or inhalation, but also by skin absorption. Phenol is soluble in water,alcohol,and ether. It is used in the production of resins,germicides,weedkillers,pharmaceuticals, and as a solvent in the refining of lubricating oils.

Production

Coal tar was once the main source of phenol, and was extracted from sodium hydroxide solution. In earlier time, people use sulfonation method to produce phenol: react sodium benzene sulfonate with sodium hydroxide to generate the sodium salt of phenol, and then treat it with acid to obtain phenol. In recent years, hydrolyzing chlorobenzene or oxidizing cumene has become the major production method. The by-product acetone in latter method is also an important industrial raw material, so oxidizing cumene is more economic industrially thus widely applied.
Cumene method:
This method generates cumene from propylene and benzene in the presence of aluminum trichloride. It oxidizes to cumene hydroperoxide and then decomposes with cation exchange resin to give phenol and acetone. For each ton of phenol produced, 0.62 tons of acetone can be produced.

Sulfonation method:
se sulfuric acid to sulfonate benzene to generate benzene sulfonic acid, neutralize it with sodium sulfite, and then undergo acidification and vacuum distillation in caustic soda solution.

Hydrogen benzene hydrolysis method: hydrogen benzene is hydrolyzed in caustic soda solution with high temperature and high pressure to generate phenol sodium, which is then neutralized to give phenol.

Definition

ChEBI: An organic hydroxy compound that consists of benzene bearing a single hydroxy substituent. The parent of the class of phenols.

Reactivity Profile

PHENOL is a weak acid. Reacts exothermically with bases. Reacts with strong oxidizing agents. Emits acrid smoke and irritating fumes when heated to decomposition. Undergoes, in the presence of aluminum chloride, potentially explosive reactions with nitromethane, butadiene, formaldehyde, peroxodisulfuric acid, peroxosulfuric acid, and sodium nitrite . Reacts violently with sodium nitrate in the presence of trifluoroacetic acid [Bretherick, 5th ed., 1995, p. 770]. May corrode lead, aluminum and its alloys, certain plastics, and rubber. Phenol may explode in contact with peroxodisulfuric acid (Dns, J. Ber., 1910, 43, 1880; Z. Anorg. Chem., 1911, 73, 1911.) or peroxomonosulfuric acid. (Sidgwick, 1950, 939)

Air & Water Reactions

Decomposes slowly in air. Mixtures of 9-10% phenol in air are explosive. Soluble in water

Fire Hazard

Flammable vapors when heated. Runoff from fire control water may give off poisonous gases and cause pollution. Mixtures of 9-10% phenol in air are explosive. Avoid aluminum chloride/nitrobenzene mixture, peroxodisulfuric acid, peroxomonosulfuric acid and strong oxidizing agents. Decomposes slowly on air contact. Avoid contact with strong oxidizing agents.

General Description

A solid melting at 110°F. Colorless if pure, otherwise pink or red. Flash point 175°F. Density 9.9 lb / gal. Vapors are heavier than air Corrosive to the skin (turning skin white) but because of its anesthetic quality numbs rather than burn. Lethal amounts can be absorbed through the skin. Used to make plastics and adhesives.

Purification Methods

Steam is passed through a boiling solution containing 1mole of phenol and 1.5-2.0moles of NaOH in 5L of H2O until all non-acidic material has distilled. The residue is cooled, acidified with 20% (v/v) H2SO4, and the phenol is separated, dried with CaSO4 and fractionally distilled under reduced pressure. It is then fractionally crystallised several times from its melt [Andon et al. J Chem Soc 5246 1960]. Purification via the benzoate has been used by Berliner, Berliner and Nelidow [J Am Chem Soc 76 507 1954]. The benzoate,(m 70o, b 314o/760mm), is crystallised from 95% EtOH, then hydrolysed to the free phenol by refluxing with two equivalents of KOH in aqueous EtOH until the solution becomes homogeneous. It is acidified with HCl and extracted with diethyl ether. The ether layer is freed from benzoic acid by thorough extraction with aqueous NaHCO3, and, after drying and removing the ether, the phenol is distilled. Phenol has also been crystallised from a 75% w/w solution in water by cooling to 11o and seeding with a crystal of the hydrate. The crystals are centrifuged off, rinsed with cold water (0-2o), saturated with phenol, and dried. It can be crystallised from pet ether [Berasconi & Paschalis J Am Chem Soc 108 2969 1986]. Draper and Pollard [Science 109 448 1949] added 12% water, 0.1% aluminium (can also use zinc) and 0.05% NaHCO3 to phenol, and distilled it at atmospheric pressure until the azeotrope was removed, The phenol was then distilled at 25mm. Phenol has also been dried by distillation from the *benzene solution to remove the water/*benzene azeotrope and the excess *benzene, followed by distillation of the phenol at reduced pressure under nitrogen. Processes such as this are probably adequate for analytical grade phenol which has as its main impurity water. Phenol has also been crystallised from pet ether/*benzene or pet ether (b 40-60o). The purified material is stored in a vacuum desiccator over P2O5 or CaSO4. [Beilstein 6 IV 531.]

Uses

Phenol is an important organic chemical raw material, widely used in the production of phenolic resin and bisphenol A, in which bisphenol A is important raw material for polycarbonate, epoxy resin, polysulfone resin and other plastics. In some cases the phenol is used to produce iso-octylphenol, isononylphenol, or isododecylphenol through addition reaction with long-chain olefins such as diisobutylene, tripropylene, tetra-polypropylene and the like, which are used in production of nonionic surfactants. In addition, it can also be used as an important raw material for caprolactam, adipic acid, dyes, medicines, pesticides and plastic additives and rubber auxiliaries.

Uses

Purified for molecular genetics applications

Description

Phenol is a stable chemical substance and appear as colourless/white crystals with a characteristic, distinct aromatic/acrid odour. It is reactive and incompatible with strong oxidising agents, strong bases, strong acids, alkalis, and calcium hypochlorite. Phenol is flammable and may discolour in light. Phenol is used in the manufacture or production of explosives, fertiliser, coke, illuminating gas, lampblack, paints, paint removers, rubber, perfumes, asbestos goods, wood preservatives, synthetic resins, textiles, drugs, and pharmaceutical preparations. It is also extensively used as a disinfectant in the petroleum, leather, paper, soap, toy, tanning, dye, and agricultural industries.

Chemical Properties

Phenol is commonly known as carbolic acid. The chemical properties of phenol are very active, and it turns to reddish crystals in the air or in contact with any impurities. It absorbs the moisture in the air and gradually liquefies in the air. Phenol is slightly soluble in water, soluble in benzene, alkaline solution and organic solvents such as ethanol, ether, chloroform, glycerol, etc. Phenol is weakly acidic and reacts with base to form salt. It appears blue when being dissolved in ferric chloride solution.

Health Hazard

Toxic hazard rating is very toxic: probable oral lethal dose (human) is 50-500 mg/kg. Ingestion of 1 gram has been lethal to humans. Lethal amounts may be absorbed through skin or inhaled. Industrial contact can cause chronic poisoning with kidney and liver damage. Persons affected with hepatic or kidney diseases are at a greater risk.
InChI:InChI=1/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H

108-95-2 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
USP (1524806)  Phenol  United States Pharmacopeia (USP) Reference Standard 108-95-2 1524806-500MG 4,588.74CNY Detail
Supelco (40063)  Phenolsolution  5000 μg/mL in methanol, certified reference material 108-95-2 000000000000040063 533.52CNY Detail
Supelco (48688)  Phenolsolution  certified reference material, 500 μg/mL in methanol 108-95-2 000000000000048688 272.61CNY Detail
Sigma-Aldrich (46344)  Phenolsolution  100 μg/mL in acetonitrile, PESTANAL®, analytical standard 108-95-2 46344-10ML 1,622.79CNY Detail
Sigma-Aldrich (46344)  Phenolsolution  100 μg/mL in acetonitrile, PESTANAL®, analytical standard 108-95-2 46344-2ML 680.94CNY Detail
Sigma-Aldrich (33517)  Phenol  puriss. p.a., ACS reagent, reag. Ph. Eur., 99.0-100.5% 108-95-2 33517-6X1KG 9,722.70CNY Detail
Sigma-Aldrich (33517)  Phenol  puriss. p.a., ACS reagent, reag. Ph. Eur., 99.0-100.5% 108-95-2 33517-1KG 2,865.33CNY Detail
Sigma-Aldrich (33517)  Phenol  puriss. p.a., ACS reagent, reag. Ph. Eur., 99.0-100.5% 108-95-2 33517-500G 1,512.81CNY Detail
Sigma-Aldrich (33517)  Phenol  puriss. p.a., ACS reagent, reag. Ph. Eur., 99.0-100.5% 108-95-2 33517-100G 655.20CNY Detail
Sigma-Aldrich (PHR1047)  Phenol  pharmaceutical secondary standard; traceable to USP and PhEur 108-95-2 PHR1047-1G 732.19CNY Detail
Sigma-Aldrich (35952)  Phenol  PESTANAL®, analytical standard 108-95-2 35952-1G 1,086.93CNY Detail
Sigma-Aldrich (35952)  Phenol  PESTANAL®, analytical standard 108-95-2 35952-500MG 627.12CNY Detail

108-95-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name phenol

1.2 Other means of identification

Product number -
Other names PHENOL

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Phenols/phenoxy acids
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:108-95-2 SDS

Please post your buying leads,so that our qualified suppliers will soon contact you!

*Required Fields