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CAS

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79547-78-7

Levocabastine hydrochloride is a potent and specific histamine H1-receptor antagonist, characterized by its fast onset and long duration of action. It is a white or almost white powder and is devoid of anticholinergic or antiserotonergic side effects. This makes it a suitable candidate for treating allergic conditions without causing unwanted side effects.

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  • 4-Piperidinecarboxylicacid, 1-[cis-4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-,hydrochloride (1:1), (3S,4R)-/ LIDE PHARMA- Factory supply / Best price

    Cas No: 79547-78-7

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  • (3S,4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenylpiperidine-4-carboxylic acid,hydrochloride

    Cas No: 79547-78-7

  • USD $ 1.9-2.9 / Gram

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  • 79547-78-7 Structure

  • Basic information

    1. Product Name: LEVOCABASTINE HYDROCHLORIDE
    2. Synonyms: R50547;LEVOPHTA;LEVOCABASTINE HCL;LEVOCABASTINE HYDROCHLORIDE;LEVOSTIN;[3S-[1(CIS),3ALPHA,4BETA]]-1-[4-CYANO-4-(4-FLUOROPHENYL)CYCLOHEXYL]-3-METHYL-4-PHENYL-4-PIPERIDINECARBOXYLIC ACID HYDROCHLORIDE;LIVOSTIN;[3s-[1(cis),3α,4β]]-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-4-piperidinecarboxylic acid
    3. CAS NO:79547-78-7
    4. Molecular Formula: C26H30ClFN2O2
    5. Molecular Weight: 456.98
    6. EINECS: N/A
    7. Product Categories: Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
    8. Mol File: 79547-78-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 611oC at 760 mmHg
    3. Flash Point: 323.3oC
    4. Appearance: white/solid
    5. Density: N/A
    6. Vapor Pressure: 8.77E-16mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: 2-8°C
    9. Solubility: DMSO: ~10 mg/mL, soluble
    10. CAS DataBase Reference: LEVOCABASTINE HYDROCHLORIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: LEVOCABASTINE HYDROCHLORIDE(79547-78-7)
    12. EPA Substance Registry System: LEVOCABASTINE HYDROCHLORIDE(79547-78-7)

  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 79547-78-7(Hazardous Substances Data)

79547-78-7 Usage

Uses

Used in Pharmaceutical Industry:
Levocabastine hydrochloride is used as a therapeutic agent for the treatment of allergic conjunctivitis and allergic rhinitis. Its application is based on its ability to effectively block histamine H1 receptors, thereby reducing the symptoms associated with these allergic conditions.

Originator

Janssen (Johnson & Johnson) (U.S.A.)

Therapeutic Function

Antihistaminic

Check Digit Verification of cas no

The CAS Registry Mumber 79547-78-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,5,4 and 7 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 79547-78:
(7*7)+(6*9)+(5*5)+(4*4)+(3*7)+(2*7)+(1*8)=187
187 % 10 = 7
So 79547-78-7 is a valid CAS Registry Number.
InChI:InChI=1/C26H29FN2O2.ClH/c1-19-17-29(16-15-26(19,24(30)31)21-5-3-2-4-6-21)23-11-13-25(18-28,14-12-23)20-7-9-22(27)10-8-20;/h2-10,19,23H,11-17H2,1H3,(H,30,31);1H/t19-,23-,25-,26-;/m1./s1

79547-78-7 Well-known Company Product Price

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  • Sigma-Aldrich

  • (L0390000)  Levocabastine hydrochloride  European Pharmacopoeia (EP) Reference Standard

  • 79547-78-7

  • L0390000

  • 1,880.19CNY

  • Detail

  • Sigma-Aldrich

  • (Y0001637)  Levocabastine for system suitability 2  European Pharmacopoeia (EP) Reference Standard

  • 79547-78-7

  • Y0001637

  • 1,880.19CNY

  • Detail

  • USP

  • (1359856)  Levocabastine hydrochloride  United States Pharmacopeia (USP) Reference Standard

  • 79547-78-7

  • 1359856-50MG

  • 5,064.93CNY

  • Detail

  • Sigma

  • (L3042)  Levocabastine hydrochloride  ≥99% (HPLC), solid

  • 79547-78-7

  • L3042-5MG

  • 2,228.85CNY

  • Detail

  • Sigma

  • (L3042)  Levocabastine hydrochloride  ≥99% (HPLC), solid

  • 79547-78-7

  • L3042-25MG

  • 8,266.05CNY

  • Detail

79547-78-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (3S,4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenylpiperidine-4-carboxylic acid,hydrochloride

1.2 Other means of identification

Product number -
Other names R 50,547

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:79547-78-7 SDS

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