- 5-Membered heterocyclic compound
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The present invention provides 5-membered heterocycle compounds represented by the following general formula (I): The present compounds have a superior acid secretion inhibitory effect, and shows an antiulcer activity and the like.
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Page/Page column 40
(2009/07/03)
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- A facile synthesis of 2,3-disubstituted furo[2,3-b]pyridines
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In a three-step sequence starting from readily available starting materials, 2,3-carbon disubstituted furo[2,3-b]pyridines can be accessed in good yields and purity. Furo[2,3-b]pyridines bearing ester, amide and ketone groups at the 2-position can be prepared with a variety of aryl and alkyl groups at the 3-position.
- Beutner, Gregory L.,Kuethe, Jeffrey T.,Yasuda, Nobuyoshi
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supporting information; experimental part
p. 781 - 784
(2009/05/11)
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- NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
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Compounds of Formula I: (I), are HIV reverse transcriptase inhibitors, wherein Q, R2, R3, R6, T1, T2, and T3 are defined herein. The compounds of Formula I, and the pharmaceutically accepta
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Page/Page column 25-26
(2008/12/06)
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- HIV reverse transcriptase inhibitors
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Compounds having the structure: are HIV reverse transcriptase inhibitors, wherein A, X, Y, Z, R1 and R2 are defined herein. The compounds and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
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Page/Page column 52-53
(2010/11/25)
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- METALLATION REGIOSELECTIVE EN SERIE PYRIDINIQUE: SYNTHESE ORIGINALE D'AMINO-2-AROYL 3-PYRIDINES
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Lithium diisopropylamide reacts with 2-fluoropyridine at low temperature: regioselectivity is excellent and metallation occurs without side reactions such as nucleophilic attack. 2-Fluoro-3-lithiopyridine is formed and with aldehydes it gives the correspo
- Guengoer, Timur,Marsais, Francis,Queguiner, Guy
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p. 139 - 150
(2007/10/02)
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