- Palladium-Catalyzed Reductive Aminocarbonylation of o-Iodophenol-Derived Allyl Ethers with o-Nitrobenzaldehydes to 3-Alkenylquinolin-2(1 H)-ones
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An attractive palladium-catalyzed reductive aminocarbonylation reaction of allylic ethers has been explored for the synthesis of 3-alkenylquinolin-2(1H)-one derivatives. With Mo(CO)6as both CO surrogate and reductant, a variety of 3-alkenylquinolin-2(1H)-ones were obtained in good to excellent yields from o-iodophenol-derived allyl ethers with o-nitrobenzaldehydes as the nitrogen sources. This reaction proceeds through a cascade pathway and does not rely on high-pressure CO gas as needed in former allylic carbonylation reactions. This strategy provides a new pathway for the construction of 3-alkenylquinolin-2(1H)-ones.
- Liu, Jian-Li,Wang, Wei,Qi, Xinxin,Wu, Xiao-Feng
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supporting information
p. 2248 - 2252
(2022/03/31)
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- Synthesis of catalytically active ruthenium complexes with a remote chiral lactam as hydrogen-bonding motif
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A terminal alkyne was prepared, which is linked by a carbon-carbon bond to a conformationally restricted, U-shaped chiral lactam, that is, more precisely, to carbon atom C7 of 1,5,7-trimethyl-3-azabicyclo[3.3.1]nonan-2-one. The alkyne was connected to var
- Voss, Felix,Vogt, Florian,Herdtweck, Eberhardt,Bach, Thorsten
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experimental part
p. 961 - 971
(2011/05/07)
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