- Allenes. Part 45. 2-Alkyltetrahydropyrimidines, 2-Alkylidenetetrahydro-2H-1,3-oxazines, 2-Alkyl-5,6-dihydro-4H-1,3-oxazines and 2-Alkyl-3-cyano-1,4,5,6-tetrahydropyridines from Allenic nitriles.
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The synthesis of 2-alkyl-3,4,5,6-tetrahydropyrimidines, 2-alkylidene-3,4,5,6-tetrahydro-2H-1,3-oxazines, 2-alkyl-5,6-dihydro-4H-1,3-oxazines and 2-alkyl-3-cyano-1,4,5,6-tetrahydropyridines from allenic nitriles is described.Spectroscopic evidence and mechanistic pathways are discussed.
- Fomum, Z. Tanee,Johnson, Andrew,Landor, Stephen R.,Landor, Phyllis D.,Mbafor, Joseph T.,Nkengfack, Augustine E.
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p. 1537 - 1553
(2007/10/02)
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- Allenes. Part 40. 2:1 Bis-adducts from Allenic Nitriles and Phenylpropynenitriles with Difunctional Nucleophiles and their Conversion into Heterocycles
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Two equivalents of allenic nitrile or phenylpropynenitrile add to 1,2- and 1,3-diamines, 2-aminoethanethiol, ethanedithiol, and 4-aminopyridine to give 2:1 adducts of structure (2), (4), and (5).Ring closure and elimination of one equivalent each of allenic nitrile (or phenylpropynenitrile) and acetonitrile gave the imidazolines (29), the thiazolines (30), and the tetrahydropyrimidines (31).Mass spectral fission patterns are discussed.
- Landor, Stephen R.,Landor, Phyllis D.,Fomum, Z. Tanee,Mbafor, J. Tanyi,Nkengfack, A. Ephraim
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p. 1223 - 1228
(2007/10/02)
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- NOVEL SYNTHESES OF DIHYDROOXAZINES, TETRAHYDROPYRIMIDINES AND TETRAHYDROPYRIDINES FROM ALLENYL NITRILES
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α-Allenylnitriles give dihydrooxazines and tetrahydropyridines with 3-hydroxypropylamine whereas with 1,3-diaminopropane they afforded tetrahydropyrimidines.
- Landor, Stephen R.,Landor, Phyllis D.,Fomum, Z. Tanee,Mbafor, J. Tanyi
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p. 1889 - 1892
(2007/10/02)
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