Compounds are described that are active on PPARs, including pan-active compounds. Also described are methods for developing or identifying compounds having a desired selectivity profile.
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Page 177-178
(2008/06/13)
AZAINDOLE DERIVATIVES. 60. NUCLEOPHILIC SUBSTITUTION REACTIONS IN 6-CHLORO-5-AZAINDOLINES
Reactions involving nucleophilic substitution of the halogen atoms in 1-benzyl-6-chloro-7-cyano-5-azaindoline by alkoxy groups and residues of varios amines were investigated.The effect of electron acceptor substituents on the saponification of the alkoxy
Azimov, V. A.,Bychikhina, N. N.,Yakhontov, L. N.
p. 1208 - 1213
(2007/10/02)
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