808755-67-1

Basic information

• Product Name: 6-Benzothiazolol,2-bromo-(9CI)
• Synonyms: 6-Benzothiazolol,2-bromo-(9CI);2-Bromo-6-Benzo[d]thiazolol;2-bromobenzo[d]thiazol-6-ol;2-broMo-1,3-benzothiazol-6-ol;2-BroMo-benzothiazol-6-ol;2-bromo-6-Benzothiazolol;2-Bromo-6-hydroxybenzothiazole
• CAS NO: 808755-67-1
• Molecular Formula: C₇H₄BrNOS
• Molecular Weight: 230.09
• Product Categories: BENZOTHIAZOLE
• Mol File: 808755-67-1.mol

Chemical Properties

• Boiling Point: 373.8 °C at 760 mmHg
• Flash Point: 179.9 °C
• Appearance: /
• Density: 1.903 g/cm³
• Vapor Pressure: 4.06E-06mmHg at 25°C
• Refractive Index: 1.768
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 8.21±0.40(Predicted)
• CAS DataBase Reference: 6-Benzothiazolol,2-bromo-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Benzothiazolol,2-bromo-(9CI)(808755-67-1)
• EPA Substance Registry System: 6-Benzothiazolol,2-bromo-(9CI)(808755-67-1)

Safety Data

• Hazardous Substances Data: 808755-67-1(Hazardous Substances Data)

Usage

Uses

2-bromobenzo[d]thiazol-6-ol is a useful research chemical.

InChI:InChI=1/C7H4BrNOS/c8-7-9-5-2-1-4(10)3-6(5)11-7/h1-3,10H

Upstream product

• 2941-58-4 2-bromo-6-methoxy-1,3 benzothiazole 
• 1747-60-0 6-methoxybenzothiazol-2-ylamine 

Downstream Products

• 1427773-38-3 2-amino-5-(ethoxymethoxy)benzenethiol 
• 1069020-23-0 4-(6-hydroxybenzo[d]thiazol-2-yl)benzonitrile 
• 945400-92-0 2-bromo-6-(tert-butyldimethylsilyloxy)benzo[d]thiazole 
• 1440526-56-6 6-benzyloxy-2-bromo-benzothiazole 

Relevant articles and documents

Multicomponent Bioluminescence Imaging with a π-Extended Luciferin

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Five new firefly luciferin (1) analogues were synthesized and their light emission properties were examined. Modifications of the thiazoline moiety in 1 were employed to produce analogues containing acyclic amino acid side chains (2–4) and heterocyclic rings derived from amino acids (5 and 6) linked to the benzothiazole moiety. Although methyl esters of all of the synthetic derivatives exhibited chemiluminescence activity, only carboluciferin (6), possessing a pyrroline-substituted benzothiazole structure, had bioluminescence (BL) activity (λmax=547 nm). Results of bioluminescence studies with AMP-carboluciferin (AMP=adenosine monophosphate) and AMP-firefly luciferin showed that the nature of the thiazoline mimicking moiety affected the adenylation step of the luciferin–luciferase reaction required for production of potent BL. In addition, BL of 6 in living mice differed from that of 1 in that its luminescence decay rate was slower.

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