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2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER is a chemical compound characterized by a piperidine ring with a benzyl ester attached to the carboxylic acid group. It is widely utilized in medicinal chemistry and pharmaceutical research as a versatile building block for the synthesis of diverse bioactive compounds. 2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER holds promise as a potential drug candidate for the treatment of neurological and psychiatric disorders, attributed to its potential to interact with neurotransmitter receptors. Its structural attributes and functional groups also render it suitable for use as an intermediate in the synthesis of other organic compounds. However, it is crucial to handle, store, and utilize this chemical with caution due to its potential health risks and environmental implications if mismanaged.

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  • 811842-18-9 Structure
  • Basic information

    1. Product Name: 2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER
    2. Synonyms: 2-AMINOMETHYL-1-N-CBZ-PIPERIDINE;2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER;1-PIPERIDINECARBOXYLIC ACID, 2-(AMINOMETHYL)-, PHENYLMETHYL ESTER;N-CBZ-2-AMINOMETHYLPIPERIDINE;2-Aminomethyl-piperidine-1-carboxylic acid benzyl esterHCl;1-Cbz-2-(aminomethyl)piperidine;1-Cbz-2-aminomethyl-piperidine HCl;Benzyl 2-(aminomethyl)piperidine-1-carboxylate
    3. CAS NO:811842-18-9
    4. Molecular Formula: C14H20N2O2
    5. Molecular Weight: 248.32
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 811842-18-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 385.7 °C at 760 mmHg
    3. Flash Point: 187.1 °C
    4. Appearance: /
    5. Density: 1.125 g/cm3
    6. Vapor Pressure: 3.73E-06mmHg at 25°C
    7. Refractive Index: 1.55
    8. Storage Temp.: 2-8°C(protect from light)
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER(811842-18-9)
    12. EPA Substance Registry System: 2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER(811842-18-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 811842-18-9(Hazardous Substances Data)

811842-18-9 Usage

Uses

Used in Pharmaceutical Research:
2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER is used as a building block for the synthesis of various bioactive compounds, contributing to the development of new pharmaceutical agents.
Used in Medicinal Chemistry:
2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER is used as a potential drug candidate for the treatment of neurological and psychiatric disorders, due to its potential interaction with neurotransmitter receptors.
Used in Organic Synthesis:
2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER is used as an intermediate in the synthesis of other organic compounds, leveraging its structural and functional group properties.
Used in Controlled Environments:
2-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER is used with caution in controlled environments to mitigate potential health hazards and environmental impact, emphasizing the importance of proper handling, storage, and usage protocols.

Check Digit Verification of cas no

The CAS Registry Mumber 811842-18-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,1,1,8,4 and 2 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 811842-18:
(8*8)+(7*1)+(6*1)+(5*8)+(4*4)+(3*2)+(2*1)+(1*8)=149
149 % 10 = 9
So 811842-18-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H20N2O2/c15-10-13-8-4-5-9-16(13)14(17)18-11-12-6-2-1-3-7-12/h1-3,6-7,13H,4-5,8-11,15H2

811842-18-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-Cbz-2-Aminomethylpiperidine

1.2 Other means of identification

Product number -
Other names benzyl 2-(aminomethyl)piperidine-1-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:811842-18-9 SDS

811842-18-9Relevant articles and documents

Active agent prodrugs with heterocyclic linkers

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Page/Page column 143; 144; 145, (2015/10/28)

The embodiments provide prodrug compounds of Formulae I-XVII. The present disclosure also provides compositions, and their methods of use, where the compositions comprise a prodrug compound of Formulae I-XVII that provides controlled release of an active agent. Such compositions can optionally provide a trypsin inhibitor that interacts with the enzyme that mediates the controlled release of an active agent from the prodrug so as to attenuate enzymatic cleavage of the prodrug.

PYRIDAZINONE DERIVATIVES AS PARP INHIBITORS

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Page/Page column 112, (2009/06/27)

The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of poly(ADP-ribose)polymerase (PARP) and thus useful for the treatment of cancer, inflammatory diseases, reperfusion injuries, ischaemic conditions, stroke, renal failure, cardiovascular diseases, vascular diseases other than cardiovascular diseases, diabetes mellitus, neurodegenerative diseases, retroviral infections, retinaldamage, skin senescence and UV-induced skin damage, and as chemo-or radiosensitizers for cancer treatment.

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