811842-30-5

Basic information

• Product Name: 2-BROMO-1-FLUORO-4-IODOBENZENE
• Synonyms: 3-BROMO-4-FLUORO IODOBENZENE;2-BROMO-1-FLUORO-4-IODOBENZENE;1-Bromo-2-fluoro-5-iodobenzene;3-Bromo-4-fluoroiodobenzene 98%;Benzene,2-broMo-1-fluoro-4-iodo-
• CAS NO: 811842-30-5
• Molecular Formula: C₆H₃BrFI
• Molecular Weight: 300.89
• Product Categories: Aromatic Halides (substituted);Bromine Compounds;Fluorine Compounds;Iodine Compounds;Fluorinated benzene series;Fluorine series
• Mol File: 811842-30-5.mol

Chemical Properties

• Boiling Point: 243℃
• Flash Point: 101℃
• Appearance: /
• Density: 2.281
• Vapor Pressure: 0.0503mmHg at 25°C
• Refractive Index: 1.628
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 2-BROMO-1-FLUORO-4-IODOBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-1-FLUORO-4-IODOBENZENE(811842-30-5)
• EPA Substance Registry System: 2-BROMO-1-FLUORO-4-IODOBENZENE(811842-30-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 811842-30-5(Hazardous Substances Data)

Usage

Chemical Properties

light yellow liquid

InChI:InChI=1/C6H3BrFI/c7-5-3-4(9)1-2-6(5)8/h1-3H

Upstream product

• 656-64-4 3-bromo-4-fluoroaniline 
• 1072-85-1 o-fluorobromobenzene 
• 701-45-1 2-bromo-1-fluoro-4-nitrobenzene 

Downstream Products

• 866686-11-5 3-(3-bromo-4-fluorophenylethynyl)-5-chloropyridine 
• 866686-54-6 3-(3-bromo-4-fluorophenylethynyl)-5-methoxypyridine 
• 1034669-84-5 6-[(3-bromo-4-fluorophenyl)ethynyl]chromane 
• 1035265-80-5 ((3-bromo-4-fluorophenyl)ethynyl)trimethylsilane 
• 1035267-65-2 4-[(3-bromo-4-fluorophenyl)ethynyI]-2,6-diethyIpyridine 
• 1035267-67-4 4-[(3-bromo-4-fluorophenyl)ethynyI]-2-methyIpyridine 
• 1062614-35-0 2-bromo-4-((4-(difluoromethoxy)-3-(2-fluoroethyl)phenyl)ethynyl)-1-fluorobenzene 
• 1083179-84-3 4-[(3-bromo-4-fluorophenyl)ethynyl]aniline 
• 1262037-84-2 4-(3-bromo-4-fluorophenyl)-3,6-dihydro-2H-pyran 
• 1228689-75-5 ethyl 2-(3-bromo-4-fluorophenyl)acetate 
• 1646842-16-1 2-(3-bromo-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1614246-28-4 4-(3-bromo-4-fluorophenyl)-7-ethyl-7H-imidazo[4,5-c]pyridazine 

Relevant articles and documents

3-((1H-PYRAZOL-4-YL)METHYL)-6'-(PHENYL)-2H-(1,2'-BIPYRIDIN)-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS GPR139 ANTAGONISTS FOR USE IN A METHOD OF TREATMENT OF E.G. DEPRESSION

The present invention refers to compounds of formula (I). The present invention also relates to compounds of formula (I) for use as G Protein coupled Receptor 139 (GPR139) antagonists in methods of medical treatment of e.g. depression, Alzheimer's disease

NOVEL TRIAZINE COMPOUND, AND ORGANIC ELECTRONIC ELEMENT AND PLANT-GROWING LIGHTING THAT USE THE SAME

PROBLEM TO BE SOLVED: To provide a triazine compound which has a high triplet energy level and excellent heat resistance, and can be used as an organic electronic element material realizing an element with high efficiency, low voltage and a long life. SOLUTION: In the triazine compound, as represented by the general formula [1] in the figure, a triazine backbone moiety is linked to a dibenzofuran or dibenzothiophene backbone moiety via a biphenyl backbone moiety, where X is an oxygen atom or sulfur atom. SELECTED DRAWING: None COPYRIGHT: (C)2018,JPO&INPIT

PYRIDYL DERIVATIVES AND THEIR USE AS MGLU5 RECEPTOR ANTAGONISTS

The present invention is directed toward pyridyl derivatives of formula (I) as antagonists of the mGlu5 receptor. As such the compounds may be useful for treatment or prevention of disorders remedied by antagonism of the mGlu5 receptor, wherein Ar is phenyl or napthyl each of which may be substituted by one or more C1-C4 alkyl, C1-C4 alkoxy, C1-C5 acyl, halo, amino, nitro, cyano, hydroxy, C1-C5 acylamino, C1-C4 alkylsulfonylamino, mono-, di- or trifluorinated C1-C3 alkyl, substituents which may be the same or different and may bear a CONH2, CONHCH3, CON(CH3)2, CO2H, CO2CH3, OCF3, CH2NHCOCH3, CH2NH2, CH2N(CH3)2, CH2CN, CH2OH, CH2NHSO2CH3, CH2N(CH3)(CH2)2 CN, CH2N(CH3)CH(CH3)2, CH2NHCH(CH3)2, CH2NH(CH2)2CH3, CH2NHCO2R4, CH2NHCH2CH3, CH2NHCH3 NHCOC(CH3)2, or N(S(O)2CH3)2 substituent; R1 is hydrogen, halo, R4, CN, C(NOH)R3, C(NO-R4)R3, (CH)2CO2R4 , (CH2)n OR3 , COR3 , CF3,SR4 , S(O)R4, S(O)2R4, COCH2CO2R3 , NHSO2R4 , NHCOR3, C(NOR3)NH2, CH2OCOR3,(CH2)n NH2, CON(CH3)2 (CH2)nNHCO2R4 , CO2R3, CONH2, CSNH2, C(NH)NHOR3, (CH2)nN(CH3)2, or CONHNHCOR3; R2 is 1,2-ethenediyl or 1,2-ethynediyl; R3 is hydrogen or C1-C4 alkyl; R4 is C1-C4 alkyl; and n is 0, 1, 2,3 or 4; or a pharmaceutically acceptable salt thereof, or an N-oxide thereof.