BROMINATION OF 4-(2-THIENYL)THIAZOLES AND 2-(2-THIENYL)QUINOLINE
Depending on the substituent, the bromination of 4-(2-thienyl)thiazoles and 2-(2-thienyl)quinoline takes place in the 5 position of the thiophene or thiazole ring.When an amino group is present in the 2 position of the thiazole ring, bromination takes place in the 5 position of the thiazole ring.When excess brominating agent is present, a second bromine atom enters the 5 position of the free ring.
Smirnov, V. A.,Zimichev, A. V.,Lyzhova, G. A.,Lipkin, A. E.
p. 28 - 31
(2007/10/02)
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