817565-26-7

Basic information

• Product Name: benzyl 3-iodo-4-methylbenzoate
• Synonyms: benzyl 3-iodo-4-methylbenzoate
• CAS NO: 817565-26-7
• Molecular Formula: C15H13IO2
• Molecular Weight: 352.16699
• Mol File: 817565-26-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: benzyl 3-iodo-4-methylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 3-iodo-4-methylbenzoate(817565-26-7)
• EPA Substance Registry System: benzyl 3-iodo-4-methylbenzoate(817565-26-7)

Safety Data

• Hazardous Substances Data: 817565-26-7(Hazardous Substances Data)

Upstream product

• 82998-57-0 3-iodo-4-toluic acid 
• 100-39-0 benzyl bromide 

Relevant articles and documents

BETA-SUBSTITUTED BETA-AMINO ACIDS AND ANALOGS AS CHEMOTHERAPEUTIC AGENTS AND USES THEREOF

β-Substituted β-amino acids, β-substituted β-amino acid derivatives, and β-substituted β-amino acid analogs and (bio)isosteres and their use as chemotherapeutic agents are disclosed. The β-substituted β-amino acid derivatives and β-substituted β-amino acid analogs and (bio)isosteres are selective LAT1/4F2hc substrates and exhibit rapid uptake and retention in tumors expressing the LAT1/4F2hc transporter. Methods of synthesizing the β-substituted β-amino acid derivatives and β-substituted β-amino acid analogs and methods of using the compounds for treating cancer are also disclosed. The β-substituted β-amino acid derivatives and β-substituted β-amino acid analogs exhibit selective uptake in tumor cells expressing the LAT1/4F2hc transporter and accumulate in cancerous cells when administered to a subject in vivo. The β-substituted β-amino acid derivatives and β-substituted β-amino acid analogs and (bio)isosteres exhibit cytotoxicity toward several tumor types.