823222-02-2 Usage
Uses
Used in Pharmaceutical Industry:
5-chloro-2-(trifluoromethyl)nicotinic acid is used as a building block for the synthesis of pharmaceuticals due to its unique chemical properties. It serves as a starting material for the development of novel drugs and biologically active molecules, contributing to the advancement of medicinal chemistry research and drug discovery.
Used in Agrochemical Industry:
In the agrochemical industry, 5-chloro-2-(trifluoromethyl)nicotinic acid is utilized as a key component in the synthesis of agrochemicals. Its structural features and chemical properties make it a valuable asset in the development of effective and innovative products for agricultural applications.
Check Digit Verification of cas no
The CAS Registry Mumber 823222-02-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,2,3,2,2 and 2 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 823222-02:
(8*8)+(7*2)+(6*3)+(5*2)+(4*2)+(3*2)+(2*0)+(1*2)=122
122 % 10 = 2
So 823222-02-2 is a valid CAS Registry Number.
823222-02-2Relevant articles and documents
Logistic flexibility in the preparation of isomeric halopyridinecarboxylic acids
Cottet, Fabrice,Schlosser, Manfred
, p. 11869 - 11874 (2007/10/03)
Although there are many conceivable ways to funtionalize, and specifically carboxylate, 2-chloro-4-(trifluoromethyl)pyridine optionally at all three vacant positions, it is more straightforward to prepare only the 2-chloro-4- (trifluoromethyl)pyridine-3-carboxylic acid (1) from this precursor and the other 6-chloro-4-(trifluoromethyl)pyridine-2- and -3-carboxylic acids (2 and 3) from a different one, viz. 5-bromo-2-chloro-4-(trifluoromethyl)pyridine. In the same manner, it proved more convenient to convert 5-chloro-2-(trifluoromethyl) pyridine in only two of the corresponding acids (6 and 7) and to make the third one (8) from 3-bromo-5-chloro-2-(trifluoromethyl)pyridine as an alternative starting material. All model substrates for functionalization were readily accessible from the correspondingly substituted chloroiodopyridine through heavy halogen displacement by in situ generated (trifluoromethyl)copper. Graphical Abstract
