827-44-1

Basic information

• Product Name: 5-CHLORO-3-PHENYL-1,2,4-OXADIAZOLE
• Synonyms: 5-CHLORO-3-PHENYL-1,2,4-OXADIAZOLE;5-chloro-3-phenyl-1,2,4-oxadiazole(SALTDATA: FREE);3-Phenyl-5-chloro-1,2,4-oxadiazole;1,2,4-Oxadiazole, 5-chloro-3-phenyl-
• CAS NO: 827-44-1
• Molecular Formula: C₈H₅ClN₂O
• Molecular Weight: 180.59
• Mol File: 827-44-1.mol

Chemical Properties

• Melting Point: 37-38℃
• Boiling Point: 110 °C(Press: 15 Torr)
• Appearance: /
• Density: 1.328±0.06 g/cm3 (20 ºC 760 Torr)
• Refractive Index: 1.564
• PKA: -3.87±0.30(Predicted)
• CAS DataBase Reference: 5-CHLORO-3-PHENYL-1,2,4-OXADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-3-PHENYL-1,2,4-OXADIAZOLE(827-44-1)
• EPA Substance Registry System: 5-CHLORO-3-PHENYL-1,2,4-OXADIAZOLE(827-44-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 827-44-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Chloro-3-phenyl-1,2,4-oxadiazole is used as a key intermediate in the synthesis of pharmaceuticals for its potential to contribute to the development of new drugs and biologically active compounds. Its unique structural properties allow it to be incorporated into various medicinal molecules, enhancing their therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Chloro-3-phenyl-1,2,4-oxadiazole is utilized as an intermediate in the production of agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals that can protect crops and enhance yield.
Used in Organic Synthesis:
5-Chloro-3-phenyl-1,2,4-oxadiazole is employed as a building block in organic synthesis, where it serves as a fundamental component in the creation of a diverse array of chemical compounds. Its presence in these syntheses can lead to the development of novel materials with specific properties for various applications.

InChI:InChI=1/C8H5ClN2O/c9-8-10-7(11-12-8)6-4-2-1-3-5-6/h1-5H

Upstream product

• 3472-76-2 (dichloro-phenyl-methyl)-carbonimidic acid dichloride 
• 1456-22-0 3-phenyl-1,2,4-oxadiazol-5-ol 
• 10026-13-8 phosphorus pentachloride 
• 10242-38-3 2-hydroxyimino-2-phenyl-acetohydroximoyl chloride 
• 10025-87-3 trichlorophosphate 
• 613-92-3 N-hydroxybenzamidine 

Downstream Products

• 3201-47-6 3-phenyl-5-methoxy-1,2,4-oxadiazole 
• 28992-40-7 1-(3-phenyl-[1,2,4]oxadiazol-5-yl)-1H-benzo[1,2,3]triazole 
• 64734-25-4 5-oxiranylmethoxy-3-phenyl-[1,2,4]oxadiazole 
• 16219-35-5 N-ethyl-3-phenyl-1,2,4-oxadiazol-5-amine 
• 16219-34-4 N,N-dimethyl-3-phenyl-1,2,4-oxadiazol-5-amine 
• 50317-01-6 N,N'-bis-(3-phenyl-[1,2,4]oxadiazol-5-yl)-propane-1,3-diamine 
• 52512-64-8 3-phenyl-5-(N'-phenyl-hydrazino)-[1,2,4]oxadiazole 
• 16219-33-3 5-methylamino-3-phenyl-1,2,4-oxadiazole 
• 16219-33-3 methyl-(3-phenyl-[1,2,4]oxadiazol-5-yl)-amine 
• 16219-36-6 N-benzyl-3-phenyl-1,2,4-oxadiazol-5-amine 
• 49772-93-2 5-benzyloxy-3-phenyl-1,2,4-oxadiazole 
• 78414-68-3 1,1-dimethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)hydrazine 
• 78414-67-2 1,2-dimethyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)hydrazine 
• 78414-66-1 1-methyl-1-(3-phenyl-1,2,4-oxadiazol-5-yl)hydrazine 

Relevant articles and documents

COMPOUNDS AND USES THEREOF

The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.