82779-14-4

Basic information

• Product Name: acetamidofluorescein
• Synonyms: acetamidofluorescein
• CAS NO: 82779-14-4
• Molecular Formula: C22H15NO6
• Molecular Weight: 389.3576
• Mol File: 82779-14-4.mol

Chemical Properties

• Boiling Point: 748.7°Cat760mmHg
• Flash Point: 406.6°C
• Appearance: /
• Density: 1.59g/cm³
• CAS DataBase Reference: acetamidofluorescein(CAS DataBase Reference)
• NIST Chemistry Reference: acetamidofluorescein(82779-14-4)
• EPA Substance Registry System: acetamidofluorescein(82779-14-4)

Safety Data

• Hazardous Substances Data: 82779-14-4(Hazardous Substances Data)

Upstream product

• 3326-34-9 fluoresceinamine 
• 75-36-5 acetyl chloride 
• 82779-12-2 3',6'-bis(acetoxy)-6-acetamidospiro[benzo[2,3-c]furan-1(3H),9'-[9H]-xanthen]-3-one 
• 108-24-7 acetic anhydride 

Relevant articles and documents

Preparation and properties of fluorescent glycosaminoglycuronans labeled with 5-aminofluorescein.

The uronic acid residues of all known glycosaminoglycuronans reacted with 5-aminofluorescein to yield fluorescent glycosaminoglycuronan derivatives, which showed fluorescence characteristics identical to those of fluorescein or 5-acetamidofluorescein. The fluorescent products could be purified by chromatography on Octyl-Sepharose; three preparations of labeled chondroitin 6-sulfate having different degrees of substitution, and a labeled heparin were obtained. Fluorescent hyaluronic acid containing labeled and unlabeled molecules was digested with testicular hyaluronidase to give fluorescent oligosaccharides. Fluorescent chondroitin 6-sulfate was treated with chondroitinase AC to give a nonfluorescent disaccharide and minor proportion of fluorescent octasaccharide. Fluorescent heparin retained its anticoagulant activity, which was similar to that of the starting heparin; its half-life in circulating rabbit blood was 36 min (by fluorometry) and 45 min (by clotting-time assay).

A photo-responsive chemical modulation of m6A RNA demethylase FTO

The adenineN6-methylation m6A is a crucial modification that is associated with several biological functions. One of the two m6A demethylases FTO has arisen as an attractive target for the development of novel cancer thera

Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein

The FTO protein is unequivocally reported to play a critical role in human obesity and in the regulation of cellular levels of m6A modification, which makes FTO a significant and worthy subject of study. Here, we identified that fluorescein der