828918-24-7

Basic information

• Product Name: 2,6-Bis[(4R)-4,5-dihydro-4-(1-methylethyl)-5,5-diphenyl-2-oxazolyl]pyridine
• Synonyms: 2,6-Bis[(4R)-4,5-dihydro-4-(1-methylethyl)-5,5-diphenyl-2-oxazolyl]pyridine;2,6-Bis((R)-4-isopropyl-5,5-diphenyl-4,5-dihydrooxazol-2-yl)pyridine;2,6-Bis[(4R)-4,5-dihydro-4-(1-methylethyl)-5,5-diphenyl-2-oxazolyl]-pyridine, 98
• CAS NO: 828918-24-7
• Molecular Formula: C41H39N3O2
• Molecular Weight: 605.77
• Mol File: 828918-24-7.mol

Chemical Properties

• Boiling Point: 739.3 °C at 760 mmHg
• Flash Point: 400.9 °C
• Appearance: /
• Density: 1.15
• PKA: 2.75±0.70(Predicted)
• CAS DataBase Reference: 2,6-Bis[(4R)-4,5-dihydro-4-(1-methylethyl)-5,5-diphenyl-2-oxazolyl]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Bis[(4R)-4,5-dihydro-4-(1-methylethyl)-5,5-diphenyl-2-oxazolyl]pyridine(828918-24-7)
• EPA Substance Registry System: 2,6-Bis[(4R)-4,5-dihydro-4-(1-methylethyl)-5,5-diphenyl-2-oxazolyl]pyridine(828918-24-7)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 828918-24-7(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Upstream product

• 499-83-2 Pyridine-2,6-dicarboxylic acid 
• 108-86-1 bromobenzene 
• 3739-94-4 2,6-Pyridinedicarbonyl dichloride 
• 78603-95-9 1,1-diphenyl-L-valinol 

Relevant articles and documents

The Asymmetric Aza-silyl-Prins Reaction: Synthesis of Enantiopure Piperidines

The design and development of the first asymmetric aza-silyl-Prins reaction is reported, giving rise to valuable and diverse piperidines and pipecolic acid derivatives in both high yields and as single enantiomers. The creation of a novel chiral auxiliary-homoallylic amine for the aza-silyl-Prins reaction is essential to its success.

A Ce(OTf)3/PyBox catalyzed enantioselective Hosomi-Sakurai reaction of aldehydes with allyltrimethylsilane

An efficient enantioselective Hosomi-Sakurai reaction catalyzed by a chiral Ce(OTf)3/PyBox complex has been explored. In the presence of 20 mol% of a chiral catalytic complex prepared in situ from Ce(OTf)3 and 2,6-bis[(S)-4-isopropyl

Enantioselective oxidation of olefins catalyzed by chiral copper bis(oxazolinyl)pyridine complexes: A reassessment

Copper complexes of chiral tridentate pybox ligands synthesized using a modified procedure have been studied as catalysts for the enantioselective allylic oxidation of olefins. A variety of olefins have been used in this reaction. Using 5 mol% of a Cu(II)

Asymmetric Kharasch Reaction: Catalytic Enantioselective Allylic Oxidation of Olefins Using Chiral Pyridine Bis(diphenyloxazoline) - Copper Complexes and tert-Butyl Perbenzoate

Copper complexes of chiral pyridine bis(diphenyloxazoline)-type ligands have been studied as catalysts for the enantioselective allylic oxidation of olefins. Using 2.5-5 mol % of these chiral catalysts and tert-butyl perbenzoate as oxidant, optically active allylic benzoates were obtained in up to 86% ee. A variety of copper salts was studied under different conditions and in different solvents. Acetone was found to be a superior solvent for the reaction. Use of phenylhydrazine in conjunction with the chiral copper complex played a crucial role in increasing the rate of the reaction. Use of 4 ? molecular sieves increased the optical yield of product in almost every case.

Synthesis of homochiral bis(oxazolinyl)pyridine type ligands for asymmetric cyclopropanation reactions

Homochiral bis(oxazolinyl)pyridine type ligands were synthesized from (S)-valine and converted into their Cu(II) complexes. Reduction of these Cu(II) complexes into Cu(I) with diazoesters was studied by uv-vis and epr spectroscopy. The enantioselective cy