Anti-tumor and proapoptotic effect of novel synthetic benzophenone analogues in Ehrlich ascites tumor cells
A series of substituted benzophenone analogues, (2-aroyl-4-methylphenoxy) acetamides 4a-e, have been synthesized via three-step synthesis sequence beginning with the 2-hydroxybenzophenones 1a-e in excellent yield. 1a-e on reaction with ethyl chloroacetate
Synthesis and tumor inhibitory activity of novel coumarin analogs targeting angiogenesis and apoptosis
A sequence of coumarin analogs 5a-j was obtained by multi step synthesis from hydroxy benzophenones (1a-j). The in vitro antiproliferative effect of the title compounds was tested against Ehrlich ascites carcinoma (EAC) and Daltons lymphoma ascites (DLA)
Vijay Avin,Thirusangu, Prabhu,Lakshmi Ranganatha,Firdouse, Aiyesha,Prabhakar,Khanum, Shaukath Ara
p. 211 - 221
(2014/03/21)
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