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844694-83-3

5,6-Dimethoxy-2-[(4-piperidyl)methyl]indane (Donepezil Impurity) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 844694-83-3 Structure

  • Basic information

    1. Product Name: 5,6-Dimethoxy-2-[(4-piperidyl)methyl]indane (Donepezil Impurity)
    2. Synonyms: 5,6-Dimethoxy-2-[(4-piperidyl)methyl]indane (Donepezil Impurity);4-[(2,3-Dihydro-5,6-diMethoxy-1H-inden-2-yl)Methyl]piperidine;4-((5,6-dimethoxy-2,3-dihydro-1H-inden-2-yl)methyl)piperidine
    3. CAS NO:844694-83-3
    4. Molecular Formula: C17H25NO2
    5. Molecular Weight: 275.3859
    6. EINECS: N/A
    7. Product Categories: Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
    8. Mol File: 844694-83-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 403.1±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.048±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 10?+-.0.10(Predicted)
    10. CAS DataBase Reference: 5,6-Dimethoxy-2-[(4-piperidyl)methyl]indane (Donepezil Impurity)(CAS DataBase Reference)
    11. NIST Chemistry Reference: 5,6-Dimethoxy-2-[(4-piperidyl)methyl]indane (Donepezil Impurity)(844694-83-3)
    12. EPA Substance Registry System: 5,6-Dimethoxy-2-[(4-piperidyl)methyl]indane (Donepezil Impurity)(844694-83-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 844694-83-3(Hazardous Substances Data)

844694-83-3 Usage

Chemical Properties

Yellow Solid

Check Digit Verification of cas no

The CAS Registry Mumber 844694-83-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,4,4,6,9 and 4 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 844694-83:
(8*8)+(7*4)+(6*4)+(5*6)+(4*9)+(3*4)+(2*8)+(1*3)=213
213 % 10 = 3
So 844694-83-3 is a valid CAS Registry Number.

844694-83-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-[(5,6-Dimethoxy-2,3-dihydro-1H-inden-2-yl)methyl]piperidine

1.2 Other means of identification

Product number -
Other names PIP056

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:844694-83-3 SDS

844694-83-3Upstream product

844694-83-3Relevant articles and documents

A new commercially viable synthetic route for donepezil hydrochloride: Anti-Alzheimer's drug

Dubey, Shailendra Kumar,Kharbanda, Manita,Dubey, Sushil Kumar,Mathela, Chandra Shekhar

experimental part, p. 1157 - 1160 (2010/11/18)

An economical new process has been developed for the synthesis of donepezil hydrochloride (1) an anti-Alzheimer's drug. The process involves Darzen reaction of pyridine-4-carboxaldehyde and 2-bromo-5,6-dimethoxy indanone affording epoxide 5,6-dimethoxy-3-(pyridine-4-yl)spiro[indene-2,2′-oxiran] -1(3H)-one (4) as a key intermediate. The one-pot deoxygenation of 4 and hydrogenation of the aryl moiety in high yield improved the overall yield of the process.

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